The emergence of highly resistant and hypervirulent Klebsiella pneumoniae CC14 clone in a tertiary hospital over 8 years

S Hala, M Malaikah, J Huang, W Bahitham, O Fallatah… - Genome Medicine, 2024 - Springer
Background Klebsiella pneumoniae is a major bacterial and opportunistic human pathogen,
increasingly recognized as a healthcare burden globally. The convergence of resistance …

A high‐resolution genomic analysis of multidrug‐resistant hospital outbreaks of Klebsiella pneumoniae

H Chung The, A Karkey, D Pham Thanh… - EMBO molecular …, 2015 - embopress.org
Multidrug‐resistant (MDR) Klebsiella pneumoniae has become a leading cause of
nosocomial infections worldwide. Despite its prominence, little is known about the genetic …

The Dissemination of Multidrug-Resistant and Hypervirulent Klebsiella pneumoniae Clones Across the Kingdom of Saudi Arabia

A Alhejaili, UH Alkherd, AA Safran Alzaidi, AAA Rajeh… - medRxiv, 2024 - medrxiv.org
Abstract The Gram-negative bacterium Klebsiella pneumoniae is a major human health
threat underlying a broad range of community-and hospital-associated infections. The …

An emerging clone (ST2096) of Klebsiella pneumoniae clonal complex 14 with enhanced virulence causes an outbreak in Saudi Arabia

S Hala, CP Antony, M Alshehri, A Alsaedi… - 2020 - repository.kaust.edu.sa
Nosocomial infections caused by multidrug-resistant (MDR) Klebsiella pneumoniae strains
represent a growing threat that needs to be addressed urgently. The principal pathogenic …

Whole-genome sequencing and comparative genomics analysis of a newly emerged multidrug-resistant Klebsiella pneumoniae isolate of ST967

J Sheng, R Cave, MM Ter-Stepanyan… - Microbiology …, 2023 - Am Soc Microbiol
Klebsiella pneumoniae is a common cause of hospital-and community-acquired infections
globally, yet its population structure remains unknown for many regions, particularly in low …

Genomic insights into the diversity, virulence and resistance of Klebsiella pneumoniae extensively drug resistant clinical isolates

AHY Lee, WF Porto, C de Faria Jr… - Microbial …, 2021 - microbiologyresearch.org
Klebsiella pneumoniae has been implicated in wide-ranging nosocomial outbreaks, causing
severe infections without effective treatments due to antibiotic resistance. Here, we …

Genomic evolution and local epidemiology of Klebsiella pneumoniae from a major hospital in Beijing, China, over a 15 year period: dissemination of known and …

M Palmieri, KL Wyres, C Mirande… - Microbial …, 2021 - microbiologyresearch.org
Klebsiella pneumoniae is a frequent cause of nosocomial and severe community-acquired
infections. Multidrug-resistant (MDR) and hypervirulent (hv) strains represent major threats …

Large-scale genomic analysis of global Klebsiella pneumoniae plasmids reveals multiple simultaneous clusters of carbapenem-resistant hypervirulent strains

A Spadar, J Perdigão, S Campino, TG Clark - Genome medicine, 2023 - Springer
Abstract Background Klebsiella pneumoniae (Kp) Gram-negative bacteria cause
nosocomial infections and rapidly acquire antimicrobial resistance (AMR), which makes it a …

A panel of diverse Klebsiella pneumoniae clinical isolates for research and development

MJ Martin, W Stribling, AC Ong… - Microbial …, 2023 - microbiologyresearch.org
Klebsiella pneumoniae are a leading cause of healthcare-associated infections worldwide.
In particular, strains expressing extended-spectrum β-lactamases (ESBLs) and …

Metagenomic approaches reveal strain profiling and genotyping of Klebsiella pneumoniae from hospitalized patients in China

J Liu, Z Xu, H Li, F Chen, K Han, X Hu… - Microbiology …, 2022 - Am Soc Microbiol
Klebsiella pneumoniae is a leading cause of highly drug-resistant infections in hospitals
worldwide. Strain-level bacterial identification on the genetic determinants of multidrug …