Associations between total cerebral blood flow and age related changes of the brain

ACGM van Es, J van der Grond, VH ten Dam… - PloS one, 2010 - journals.plos.org
Background and Purpose Although total cerebral blood flow (tCBF) is known to be related to
age, less is known regarding the associations between tCBF and the morphologic changes …

Total cerebral blood flow, white matter lesions and brain atrophy: the SMART-MR study

APA Appelman, Y Van der Graaf… - Journal of Cerebral …, 2008 - journals.sagepub.com
We investigated whether total cerebral blood flow (CBF) was associated with brain atrophy,
and whether this relation was modified by white matter lesions (WML). Within the Second …

Longitudinal Changes in Global Cerebral Blood Flow in Cognitively Normal Older Adults: A Phase‐Contrast MRI Study

H Han, Z Lin, A Soldan, C Pettigrew… - Journal of Magnetic …, 2022 - Wiley Online Library
Background Characterization of blood supply changes in older individuals is important in
understanding brain aging and diseases. However, prior studies largely focused on cross …

[引用][C] Cerebral blood flow in aging

PH Dupui, A Güell, G Bessoles, G Géraud… - Effects of aging on …, 1984 - karger.com
Results Evolution of Mean CBF Values According to Age The mean CBF values recorded
were as follows: cortical CBF (Fl)= 80.1 14.2 ml/100g/min; ISI= 48.5 9.7. Our subjects …

Lower cerebral blood flow is associated with faster cognitive decline in Alzheimer's disease

MR Benedictus, AE Leeuwis, MAA Binnewijzend… - European …, 2017 - Springer
Objective To determine whether lower cerebral blood flow (CBF) is associated with faster
cognitive decline in patients with Alzheimer's disease (AD). Methods We included 88 …

Reduced parenchymal cerebral blood flow is associated with greater progression of brain atrophy: the SMART-MR study

R Ghaznawi, MHT Zwartbol… - Journal of Cerebral …, 2021 - journals.sagepub.com
Global cerebral hypoperfusion may be involved in the aetiology of brain atrophy; however,
long-term longitudinal studies on this relationship are lacking. We examined whether …

Influence of blood viscosity to cerebral blood flow in older humans compared to young subjects

RF Santos-Galduróz, OFA Bueno, LI Yamaga… - Clinical …, 2012 - Elsevier
OBJECTIVE: Since blood viscosity (BV) is one of the most important factors determining
blood flow, this study aimed to investigate the possible correlation between increased blood …

The bidirectional association between reduced cerebral blood flow and brain atrophy in the general population

HI Zonneveld, EA Loehrer, A Hofman… - Journal of Cerebral …, 2015 - journals.sagepub.com
The question remains whether reduced cerebral blood flow (CBF) leads to brain atrophy or
vice versa. We studied the longitudinal relation between CBF and brain volume in a …

Evidence of an association between cerebral blood flow and microstructural integrity in normative aging using a holistic MRI approach

M Kiely, C Triebswetter, Z Gong… - Journal of Magnetic …, 2023 - Wiley Online Library
Background Cerebral tissue integrity decline and cerebral blood flow (CBF) alteration are
major aspects of motor and cognitive dysfunctions and neurodegeneration. However, little is …

Total cerebral blood flow and total brain perfusion in the general population: the Rotterdam Scan Study

MW Vernooij, A Van der Lugt… - Journal of Cerebral …, 2008 - journals.sagepub.com
Reduced cerebral perfusion may contribute to the development of cerebrovascular and
neurodegenerative diseases. Little is known on cerebral perfusion in the general population …