Arterial hypertension continues to be the leading cause of death worldwide 1, 2 and,
unfortunately, remains uncontrolled in a significant percentage of hypertensive patients who …

The article presents a literature review on effectiveness, safety and impact on prognosis of
candesartan use in patients with hypertension, diabetes mellitus, and chronic kidney …

Valsartan/hydrochlorothiazide is a fixed-dose (valsartan 80, 160 or 320mg plus
hydrochlorothiazide 12.5 or 25mg) angiotensin II receptor blocker/diuretic drug combination …

The development of angiotensin II (Ang II) receptor antagonists is one of the latest advances
in the pharmacological treatment of hypertension and other related diseases. Since the …

Valsartan is used as a hypertension therapy that reduces blood pressure by inhibiting the
activity of angiotensin II only at the AT1 receptor, hence it is also called ARB (angiotensin …

Objective: To compare the efficacy, safety and tolerability of valsartan to an angiotensin-
converting enzyme (ACE) inhibitor, lisinopril, and placebo in patients with mild-to-moderate …

Objective: This study compared the efficacy and tolerability of two combination regimens of
valsartan and hydrochlorothiazide (HCTZ) with valsartan monotherapy in patients with …

A multicenter, randomized, placebo-controlled, double-masked, parallel-group study was
performed to compare the efficacy and safety of valsartan 20, 80, 160, and 320 mg with …

The PARADIGM-HF study demonstrated the efficacy of angiotensin receptor neprilysin
inhibitor in patients with chronic heart failure secondary to left ventricular systolic …

Synopsis Valsartan competitively and selectively inhibits the actions of angiotensin II at the
AT 1 receptor subtype which is responsible for most of the known effects of angiotensin II. In …