INTRODUCTION Myeloid cells are highly heterogeneous, with distinct ontogenies and
immune functions. The diverse role of myeloid populations, including monocytes …

Innate immune cells recruited to inflammatory sites have short life spans and originate from
the marrow, which is distributed throughout the long and flat bones. While bone marrow …

It remains unclear how immune cells from skull bone marrow niches are recruited to the
meninges. Here we report that cerebrospinal fluid (CSF) accesses skull bone marrow via …

The central nervous system (CNS) and its meningeal coverings accommodate a diverse
myeloid compartment that includes parenchymal microglia and perivascular macrophages …

Decades of research have characterized diverse immune cells surveilling the CNS. More
recently, the discovery of osseous channels (so-called 'skull channels') connecting the …

INTRODUCTION The meninges are a three-layer membrane that covers the central nervous
system (CNS): The outermost layer, the dura mater, is attached onto the skull periosteum; …

The bone marrow in the skull is important for shaping immune responses in the brain and
meninges, but its molecular makeup among bones and relevance in human diseases …

Interactions between the immune and central nervous systems strongly influence brain
health. Although the blood–brain barrier restricts this crosstalk, we now know that meningeal …

Myeloid cells in the central nervous system (CNS) represent a heterogeneous class of
innate immune cells that contribute to the maintenance of tissue homeostasis differentially …

The CNS is protected by the immune system, including cells that reside directly within the
CNS and help to ensure proper neural function, as well as cells that traffic into the CNS with …