Highlights•Dietary changes alter the composition and function of the microbiome.•Trans-
kingdom microbial interactions shape airway inflammation.•Microbial-derived metabolites …

Air pollution represents a significant public health concern worldwide. Inhalation of air
pollutants such as diesel exhaust induces oxidative stress and inflammation in the airways …

The introduction of 16s ribosomal RNA sequencing as a nonculture technique has led to the
discovery of the presence of microbiota in the lower airways of healthy individuals. These …

Simple Summary Lung cancer is the major cause of cancer related deaths in the world. New
therapies have improved outcomes. Unfortunately, overall 5 year survival is~ 20 …

Iron is an essential micronutrient for nearly all living organisms. In addition to facilitating
redox reactions, iron is bound by metalloproteins that participate in a variety of biological …

The lungs were long thought to be sterile until technical advances uncovered the presence
of the lung microbial community. The microbiome of healthy lungs is mainly derived from the …

Trace metal elements, such as iron, copper, manganese, and zinc, are essential nutrients for
biological processes. Although their intake demand is low, they play a crucial role in cell …

The human respiratory tract, usually considered sterile, is currently being investigated for
human-associated microbial communities. According to Dickson's conceptual model, the …

Host− microbiota interaction plays fundamental roles in the homeostasis of mucosal
immunity. Dysbiosis of intestinal microbiota has been demonstrated to participate in various …

Copper is universally toxic in excess, a feature exploited by the human immune system to
facilitate bacterial clearance. The mechanism of copper intoxication remains unknown for …