Introduction A significant advance in evaluation of gastric function occurred in 1943 when
the quantitative measurement of the fasting gastric secretion of acid was first applied …

Dose-response studies to tetragastrin were performed in patients with duodenal ulcer before
and after highly selective vagotomy, hemigastrectomy and truncal vagotomy plus …

The rate of evacuation of water from the stomach was found to be significantly increased by
vagotomy and drainage procedure. The rate was not affected by the type of drainage …

BRITISH MEDICAL JOURNAL Page 1 BRITISH MEDICAL JOURNAL LONDON SATURDAY
JUNE 3 1961 EFFECT OF MEDICAL AND SURGICAL VAGOTOMY ON THE AUGMENTED …

THE operation of vagotomy, reintroduced by Dragstedt in 1945, has for some time now been
accepted as a form of treatment for duodenal ulcer (Slaney, Bevan, and Brooke, 1956; Holt …

Preoperative acid studies and early postoperative insulin tests in 275 patients undergoing
various forms of vagotomy have been related to recurrent ulceration. Follow-up time has …

METHODS THE AUGMENTED HISTAMINE TEST (KAY, 1953; MARKS, BANK, LOUW, AND
VAN EMBDEN, 1962) A radioopaque nasogastric tube was positioned into the dependent …

SUMMARY A combined pentagastrin/insulin test is described. The results obtained using
this test in 220 patients before surgery, IOO patients 6 or more weeks after vagotomy, and 44 …

Twenty‐four‐hour gastric pH measurement was used to study duodenogastric reflux. To
differentiate between gastric hyposecretion and duodenogastric reflux, we also measured …

Basal acid output (BAO) and Maximal acid outputs (MAO) were measured 5 years after
highly selective vagotomy (HSV) in 21 patients who had previously undergone serial testing …