A large osteopenic animal model that resembles human osteoporotic changes is essential
for osteoporosis research. This study aimed at establishing a large osteopenic animal model …

Osteoporosis is a global problem which results in increased fractures risk. The reports from
earlier studies were inconsistent with the aging factor as well as the time which is needed to …

Introduction Experimental models of osteoporosis in rabbits are useful to investigate
anabolic agents because this animal has a fast bone turnover with predominant remodelling …

ObjectiveTo dynamically assess the regular pattern of both bone quantity and bone quality
by means of MR spectroscopey and Micro-CT scanning in an osteoporosis rabbit model …

Osteons are the structure and the base foundation of the human skeletal system. This
cylindrical structure contains blood vessels and nerves that supply the bone matrix in …

Osteoporosis is an important systemic disorder, affecting mainly Caucasian women, with a
diverse and multifactorial etiology. A large variety of animal species, including rodents …

BACKGROUND: In vertebrae, the amount of cortical bone has been estimated at 30–60%,
but 45–75% of axial load on a vertebral body is borne by cortical bone. OBJECTIVE: To …

The study aims to evaluate a standardized Sprague-Dawley (SD) rat model for
postmenopausal osteoporosis (PMO) research, including the selection of animals, surgical …

Estrogen‐depletion bone‐loss studies often use ovariectomized (ovx) rats and measure
bone mineral density in vivo or ex vivo using DXA. Recently, a portable densitometer …

Background Bone mass density is an important parameter used in the estimation of the
severity and depth of lesions in osteoporosis. Estimation of bone density using existing …