In comparison with the number of antibacterial drugs available, there are far fewer antifungal
compounds. Even so the number of antifungal drugs is increasing all the time. There are four …

Treating human fungal infections by chemicals and medicinal plant extracts is a century-old
tradition. Potassium iodide was first introduced as an antifungal agent in 1903. This was …

In this chapter, currently available topical and systemic antifungal agents (polyenes, azoles,
echinocandins, allylamines, antimetabolites) are reviewed. The mechanism of action …

Although the existence of fungi is necessary for the balance of ecosystems, over the period
of time, it is apparent that some of the fungi are capable of causing some serious infections …

For more than two decades, amphotericin B has been the single broad-spectrum agent for
the treatment of systemic mycoses. Amphotericin B is not always effective, must be given …

The last decade has witnessed remarkable advances in the therapy for cutaneous fungal
diseases. These will have a major impact on the choice of antifungal therapy. To understand …

As long ago as 1665 thrush was recorded as being a fatal disease; this was at a time when
Robert Hooke was describing for the first time the microscopic appearance of fungi [1]. While …

The most relevant information on the present state of the art of antifungal chemotherapy is
reviewed in this chapter. For dermatomycoses a variety of topical antifungals are available …

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Until about 25 years ago there was a limited choice of drugs which were effective against
pathogenic fungi. These included the earliest of the topically active compounds such as …