Genistein, a natural isoflavonoid phyto-oestrogen, inhibits the tyrosine kinase activity of
growth factor receptors and oncogene products, as well as the in vitro growth of some …

Genistein, a prominent isoflavone in soy products, produced dose-and time-dependent in
vitro growth inhibition at high concentrations (at least 185 μM) with an IC 50 of 7.0–274.2 μM …

Genistein is thought to contribute to the putative breast cancer preventive activity of soya.
The mechanisms by which it arrests the growth of breast cells are incompletely understood …

Genistein, found in soy products, is a phytochemical with several biological activities. In the
current study, our research focused on the estrogenic and proliferation-inducing activity of …

Genistein significantly inhibited cell growth (IC50 around 10 μM) of MCF-7, MDAMB-231 and
HBL-100 cell lines, but not of skin-derived fibroblasts and counteracted the growth …

The studies presented were conducted to assess the effect of the soy isoflavone genistein
on proliferation of estrogen-independent human breast cancer cells (MDA-MB-231) in vitro …

Experimental and epidemiologic studies support the view that soyfoods prevent cancer as
well as diseases and symptoms associated with estrogen deficiency. Recent research …

Aim: The aim of the present study was to identify the mechanism by which genistein and 17β-
estradiol inhibit proliferation of MDA-MB-231 breast cancer cells. Materials and Methods …

Physiological concentration of genistein, a natural isoflavonoid phytoestrogen, stimulates
human breast cancer (MCF-7) cells proliferation. In this study, we hypothesize that low …

Abstract Background/Aim: Genistein, a soy component, has been shown to have a biphasic
proliferative effect in breast cancer cells, inhibiting in vitro cell proliferation at high …