Induction of cellular immune responses against carcinoembryonic antigen in patients with metastatic tumors after vaccination with altered peptide ligand-loaded …

J Babatz, C Röllig, B Löbel, G Folprecht… - Cancer Immunology …, 2006 - Springer
Abstract Purpose: Dendritic cells (DCs) are characterized by their extraordinary capacity to
induce T-cell responses, providing the opportunity of DC-based cancer vaccination …

[HTML][HTML] Vaccination of colorectal cancer patients with CEA-loaded dendritic cells: antigen-specific T cell responses in DTH skin tests

WJ Lesterhuis, IJM De Vries, DH Schuurhuis… - Annals of …, 2006 - Elsevier
Abstract Background Dendritic cells (DCs) are the professional antigen-presenting cells of
the immune system. As such they are currently used in clinical vaccination protocols in …

Induction of tumor-specific T-cell responses by vaccination with tumor lysate-loaded dendritic cells in colorectal cancer patients with carcinoembryonic-antigen positive …

A Tamir, E Basagila, A Kagahzian, L Jiao… - Cancer Immunology …, 2007 - Springer
Abstract Background Dendritic cells (DCs) are the most effective antigen-presenting cells. In
the last decade, the use of DCs for immunotherapy of cancer patients has been vastly …

A Phase I study of active immunotherapy with carcinoembryonic antigen peptide (CAP-1)-pulsed, autologous human cultured dendritic cells in patients with metastatic …

MA Morse, Y Deng, D Coleman, S Hull… - Clinical Cancer …, 1999 - AACR
Abstract Dendritic cells (DCs), antigen-presenting cells capable of priming naive T cells to
specific antigens in an HLA-restricted fashion, have been demonstrated to induce protective …

Vaccination of metastatic colorectal cancer patients with matured dendritic cells loaded with multiple major histocompatibility complex class I peptides

B Kavanagh, A Ko, A Venook, K Margolin… - Journal of …, 2007 - journals.lww.com
Developing a process to generate dendritic cells (DCs) applicable for multicenter trials
would facilitate cancer vaccine development. Moreover, targeting multiple antigens with …

Dendritic cells in vaccination therapies of malignant diseases

MDP Brossart - Transfusion and Apheresis Science, 2002 - Elsevier
Dendritic cells (DC) are the most potent APC with the unique capacity to initiate primary
immune responses. For clinical use DC can be generated in vitro from CD34+ peripheral …

Induction of carcinoembryonic antigen (cea)‐specific cytotoxic t‐lymphocyte responses In vitro using autologous dendritic cells loaded with cea peptide or cea rna in …

SK Nair, S Hull, D Coleman, E Gilboa… - … journal of cancer, 1999 - Wiley Online Library
The application of dendritic cells (DC) to the active immunotherapy of cancer currently relies
on the generation of potent DC capable of presenting tumor antigens such as …

Bone marrow-derived dendritic cells serve as potent adjuvants for peptide-based antitumor vaccines

JI Mayordomo, T Zorina, WJ Storkus, L Zitvogel… - Stem …, 1997 - academic.oup.com
Dendritic cells (DCs) are considered the most effective antigen-presenting cells (APCs) for
primary immune responses. Since presentation of antigens to the immune system by …

The use of dendritic cells for peptide-based vaccination in cancer immunotherapy

ML Salem - Cancer vaccines: methods and protocols, 2014 - Springer
Effective antitumor immunity requires the generation and persistence of functional tumor-
specific T-cell responses. Among the critical factors that often control these responses is how …

Immunogenicity of dendritic cells pulsed with CEA peptide or transfected with CEA mRNA for vaccination of colorectal cancer patients

WJ Lesterhuis, IJM De Vries, G Schreibelt… - Anticancer …, 2010 - ar.iiarjournals.org
Background: Dendritic cells (DCs) are the professional antigen-presenting cells of the
immune system. We have demonstrated that vaccination of autologous ex vivo cultured DCs …