Cytokine production by human airway epithelial cells after exposure to an air pollution particle is metal-dependent

JD Carter, AJ Ghio, JM Samet, RB Devlin - Toxicology and applied …, 1997 - Elsevier
Despite the many epidemiological studies supporting the contention that ambient air
pollution particles can adversely affect human health, there is no clear agreement as to a …

Size-partitioning of an urban aerosol to identify particle determinants involved in the proinflammatory response induced in airway epithelial cells

K Ramgolam, O Favez, H Cachier, A Gaudichet… - Particle and Fibre …, 2009 - Springer
Background The contribution of air particles in human cardio-respiratory diseases has been
enlightened by several epidemiological studies. However the respective involvement of …

The importance of surface area and specific reactivity in the acute pulmonary inflammatory response to particles

R Duffin, CL Tran, A Clouter, DM Brown… - Annals of …, 2002 - academic.oup.com
A range of different particle types cause excessive lung inflammation that is thought to play a
role in the various types of pathology they produce. Recently attention has been focused on …

Differential particulate air pollution induced oxidant stress in human granulocytes, monocytes and alveolar macrophages

S Becker, JM Soukup, JE Gallagher - Toxicology in vitro, 2002 - Elsevier
It has been proposed that oxidant stress of cells in the lung is one of the underlying
mechanisms of particulate pollution-induced exacerbation of lung disease. Individuals who …

Temporal association between pulmonary and systemic effects of particulate matter in healthy and cardiovascular compromised rats

UP Kodavanti, MC Schladweiler… - Journal of Toxicology …, 2002 - Taylor & Francis
Exposure to particulate matter (PM) has been associated with increased morbidity and
mortality among individuals with cardiovascular disease. It is hypothesized that systemic …

The effects of ambient particulate matter on human alveolar macrophage oxidative and inflammatory responses

K Sawyer, S Mundandhara, AJ Ghio… - Journal of Toxicology …, 2009 - Taylor & Francis
Epidemiologic and occupational studies demonstrated that ambient particulate matter (PM)
and diesel exhaust particles (DEP) exert deleterious effects on human cardiopulmonary …

Differential pulmonary inflammation and in vitro cytotoxicity of size-fractionated fly ash particles from pulverized coal combustion

MI Gilmour, S O'Connor, CAJ Dick… - Journal of the Air & …, 2004 - Taylor & Francis
Exposure to airborne particulate matter (PM) has been associated with adverse health
effects in humans. Pulmonary inflammatory responses were examined in CD1 mice after …

A pilot investigation of the relative toxicity of indoor and outdoor fine particles: in vitro effects of endotoxin and other particulate properties.

CM Long, HH Suh, L Kobzik, PJ Catalano… - Environmental …, 2001 - ehp.niehs.nih.gov
In this study we assessed the in vitro toxicity of 14 paired indoor and outdoor PM (2.5)
samples (particulate matter< or= 2.5 microm in aerodynamic diameter) collected in 9 Boston …

Particle size, chemical composition, seasons of the year and urban, rural or remote site origins as determinants of biological effects of particulate matter on pulmonary …

MG Perrone, M Gualtieri, V Consonni, L Ferrero… - Environmental …, 2013 - Elsevier
Particulate matter (PM), a complex mix of chemical compounds, results to be associated with
various health effects. However there is still lack of information on the impact of its different …

Cytokine and chemokine expression patterns in lung epithelial cells exposed to components characteristic of particulate air pollution

J Øvrevik, M Låg, JA Holme, PE Schwarze, M Refsnes - Toxicology, 2009 - Elsevier
Airborne particulate matter (PM) has a complex composition, and the relative contribution of
different compounds to PM-induced effects is only partly understood. The present study …