Size-and cell type-dependent cellular uptake, cytotoxicity and in vivo distribution of gold nanoparticles

Q Xia, J Huang, Q Feng, X Chen, X Liu… - International journal …, 2019 - Taylor & Francis
Background Gold nanoparticles (AuNPs) have shown great promise in biomedical
applications. However, the interaction of AuNPs with biological systems, its underlying …

[HTML][HTML] Effects of internalized gold nanoparticles with respect to cytotoxicity and invasion activity in lung cancer cells

Z Liu, Y Wu, Z Guo, Y Liu, Y Shen, P Zhou, X Lu - PloS one, 2014 - journals.plos.org
The effect of gold nanoparticles on lung cancer cells is not yet clear. In this study, we
investigated the cytotoxicity and cell invasion activity of lung cancer cells after treatment with …

[HTML][HTML] Toxicity and biokinetics of colloidal gold nanoparticles

MR Jo, SH Bae, MR Go, HJ Kim, YG Hwang, SJ Choi - Nanomaterials, 2015 - mdpi.com
Gold nanoparticles (Au-NPs) have promising potential for diverse biological application, but
it has not been completely determined whether Au-NP has potential toxicity in vitro and in …

Size and shape-dependent cytotoxicity profile of gold nanoparticles for biomedical applications

A Woźniak, A Malankowska, G Nowaczyk… - Journal of Materials …, 2017 - Springer
Metallic nanoparticles, in particular gold nanoparticles (AuNPs), offer a wide spectrum of
applications in biomedicine. A crucial issue is their cytotoxicity, which depends greatly on …

Size-dependent toxicity and cell interaction mechanisms of gold nanoparticles on mouse fibroblasts

R Coradeghini, S Gioria, CP García, P Nativo… - Toxicology letters, 2013 - Elsevier
Gold nanoparticles (AuNPs) are currently used in several fields including biomedical
applications, although no conclusive information on their cytotoxicity is available. For this …

Effect of size, shape, and surface modification on cytotoxicity of gold nanoparticles to human HEp‐2 and canine MDCK cells

Y Zhang, D Xu, W Li, J Yu, Y Chen - Journal of Nanomaterials, 2012 - Wiley Online Library
There have been increasing interests in applying gold nanoparticles in biological research,
drug delivery, and therapy. As the interaction of gold nanoparticles with cells relies on …

[HTML][HTML] In vivo bio-distribution and acute toxicity evaluation of greenly synthesized ultra-small gold nanoparticles with different biological activities

FS Aljohani, MT Hamed, BA Bakr, YH Shahin… - Scientific reports, 2022 - nature.com
Ultra-small gold nanoparticles (Au-NPs)“≤ 10 nm diameters” have potent biomedical
applications. Hence, the present study aimed to greenly synthesize ultra-small gold …

Cytotoxicity and cellular uptake of different sized gold nanoparticles in ovarian cancer cells

D Kumar, I Mutreja, K Chitcholtan, P Sykes - Nanotechnology, 2017 - iopscience.iop.org
Nanomedicine has advanced the biomedical field with the availability of multifunctional
nanoparticles (NPs) systems that can target a disease site enabling drug delivery and …

Cell type-dependent uptake, localization, and cytotoxicity of 1.9 nm gold nanoparticles

JA Coulter, S Jain, KT Butterworth… - International journal …, 2012 - Taylor & Francis
Background This follow-up study aims to determine the physical parameters which govern
the differential radiosensitization capacity of two tumor cell lines and one immortalized …

Particle size-dependent organ distribution of gold nanoparticles after intravenous administration

WH De Jong, WI Hagens, P Krystek, MC Burger… - Biomaterials, 2008 - Elsevier
A kinetic study was performed to determine the influence of particle size on the in vivo tissue
distribution of spherical-shaped gold nanoparticles in the rat. Gold nanoparticles were …