The dichotomy of immunology into innate and adaptive immunity has created conceptual
barriers in appreciating the intrinsic two-way interaction between immune cells. An emerging …

Passive immunotherapy, including adoptive T-cell therapy and antibody therapy, has shown
encouraging results in cancer treatment lately. However, active immunotherapy of solid …

Immunity to infectious agents involves a coordinated response of innate and adaptive
immune cells working in concert, with many feed-forward and regulatory interactions …

Given recent technological advances and advances in our understanding of cancer,
immunotherapy of cancer is being used with clear clinical benefit. The immunosuppression …

Chronic inflammation in the tumor microenvironment and evasion of the antitumor effector
immune response are two of the emerging hallmarks required for oncogenesis and cancer …

Conventional anticancer therapies, such as chemotherapy, radiotherapy, and targeted
therapy, are designed to kill cancer cells. However, the efficacy of anticancer therapies is not …

Studies in tumor immunology have relied upon the classic paradigm of distinct innate and
adaptive parts of the immune system. However, recent advances in immunology suggest …

The improved understanding of the biochemical nature of tumor antigens and the
identification of cellular and molecular mechanisms leading to activation of innate and …

The recognition of the important role of cancer immunity in tumors has led to the introduction
of immunotherapeutic strategies. Most of the immunomodulatory approaches currently being …

The last decade has witnessed an exponential increase in the attempts to demonstrate that
adaptive immunity can effectively detect cancer cells and impair their growth invivo in cancer …