Highlights•Photomixotrophic production of biofuels and plastic precursors.•Novel carbon
utilization to improve cyanobacterial chemical production.•Metabolic engineering techniques …

Cyanobacterium offers a promising chassis for phototrophic production of renewable
chemicals. Although engineered cyanobacteria can achieve similar product carbon yields as …

Highlights•Metabolic engineering of cyanobacteria for biofuel and bulk chemical
production.•Photoheterotrophic production is improving titers in light and dark …

Engineering cyanobacteria into photosynthetic microbial cell factories for the production of
biochemicals and biofuels is a promising approach toward sustainability. Cyanobacteria …

Through metabolic engineering cyanobacteria can be employed in biotechnology.
Combining the capacity for oxygenic photosynthesis and carbon fixation with an engineered …

Oxygenic photosynthesis is the origin of most organic carbon compounds on Earth and an
essential part of the natural carbon cycle. Cyanobacteria, the only oxygenic …

Highlights•Concepts making direct use of light energy to drive biotransformation
reactions.•Regulatory proteins as tools to control energy and carbon fluxes in …

Biological chemical production has gained traction in recent years as a promising
renewable alternative to traditional petrochemical based synthesis. Of particular interest in …

Cyanobacteria constitute the only phylum of oxygen-evolving photosynthetic prokaryotes
that shaped the oxygenic atmosphere of our planet. Over time, cyanobacteria have evolved …

Light-driven synthetic biology refers to an autotrophic microorganisms-based research
platform that remodels microbial metabolism through synthetic biology and directly converts …