Spinal Neuropeptide Responses in Persistent and Transient Pain Following Cervical Nerve Root Injury:(Presented at the 2004 CSRS Meeting)
SM Rothman, RA Kreider, BA Winkelstein - Spine, 2005 - journals.lww.com
Study Design. Behavioral and immunohistochemical analysis in rat models of persistent and
transient allodynia. Objectives. To examine separate cervical nerve root injuries …
transient allodynia. Objectives. To examine separate cervical nerve root injuries …
Transient cervical nerve root compression in the rat induces bilateral forepaw allodynia and spinal glial activation: mechanical factors in painful neck injuries
RD Hubbard, BA Winkelstein - Spine, 2005 - journals.lww.com
Study Design. An in vivo rat model of transient cervical nerve root compression. Objectives.
To investigate the potential for cervical nerve root compression to produce behavioral …
To investigate the potential for cervical nerve root compression to produce behavioral …
Transient cervical nerve root compression modulates pain: load thresholds for allodynia and sustained changes in spinal neuropeptide expression
RD Hubbard, Z Chen, BA Winkelstein - Journal of biomechanics, 2008 - Elsevier
Nerve root compression produces chronic pain and altered spinal neuropeptide expression.
This study utilized controlled transient loading in a rat model of painful cervical nerve root …
This study utilized controlled transient loading in a rat model of painful cervical nerve root …
Neurotransmitters in the spinal cord dorsal horn in a model of painful neuropathy and in nerve crush
C Sommer, RR Myers - Acta neuropathologica, 1995 - Springer
We tested the hypothesis that neurochemical changes in the spinal cord dorsal horn
associated with neuropathic pain states differ from those seen in association with non …
associated with neuropathic pain states differ from those seen in association with non …
Neuropeptide changes persist in spinal cord despite resolving hyperalgesia in a rat model of mononeuropathy
R Munglani, SM Harrison, GD Smith, C Bountra… - Brain research, 1996 - Elsevier
We have previously described the changes in spinal cord neuropeptides in the unilateral
sciatic chronic constriction injury (CCI) model of Bennett and Xie [Pain, 33 (1988) 87–108] at …
sciatic chronic constriction injury (CCI) model of Bennett and Xie [Pain, 33 (1988) 87–108] at …
The roles of mechanical compression and chemical irritation in regulating spinal neuronal signaling in painful cervical nerve root injury
S Zhang, KJ Nicholson, JR Smith, TM Gilliland, PP Syré… - 2013 - sae.org
Both traumatic and slow-onset disc herniation can directly compress and/or chemically
irritate cervical nerve roots, and both types of root injury elicit pain in animal models of …
irritate cervical nerve roots, and both types of root injury elicit pain in animal models of …
Spinal cord injury and anti-NGF treatment results in changes in CGRP density and distribution in the dorsal horn in the rat
MD Christensen, CE Hulsebosch - Experimental neurology, 1997 - Elsevier
Spinal cord injury (SCI) results in chronic pain states in which the underlying mechanism is
poorly understood. To begin to explore possible mechanisms, calcitonin gene-related …
poorly understood. To begin to explore possible mechanisms, calcitonin gene-related …
Quantitative evaluation of calcitonin gene-related peptide and substance P levels in rat spinal cord following peripheral nerve injury
KC Kajander, J Xu - Neuroscience letters, 1995 - Elsevier
Levels of calcitonin gene-related peptide immunoreactivity (CGRP-ir) and substance P
immunoreactivity (SP-ir) in the lumbar dorsal spinal cord of rats with either sciatic nerve …
immunoreactivity (SP-ir) in the lumbar dorsal spinal cord of rats with either sciatic nerve …
Evaluation of behavior and neuropeptide markers of pain in a simple, sciatic nerve-pinch pain model in rats
K Hirose, N Iwakura, S Orita, M Yamashita… - European Spine …, 2010 - Springer
Pathomechanisms of injured-nerve pain have not been fully elucidated. Radicular pain and
chronic constriction injury models have been established; however, producing these models …
chronic constriction injury models have been established; however, producing these models …
Involvement of peripherally released substance P and calcitonin gene-related peptide in mediating mechanical hyperalgesia in a traumatic neuropathy model of the …
JH Jang, TS Nam, KS Paik, JW Leem - Neuroscience letters, 2004 - Elsevier
We hypothesized that neuropeptides released from the peripheral terminals of primary
afferents play an important role in mechanical hyperalgesia after peripheral nerve injury …
afferents play an important role in mechanical hyperalgesia after peripheral nerve injury …