New ways of understanding membranous nephropathy

H Trujillo, M Alonso, M Praga - Nephron, 2020 - karger.com
Background: In the last decade, great advances have been made in the field of membranous
nephropathy (MN). The autoimmune nature of the disease has been confirmed with the …

[HTML][HTML] Mayo Clinic consensus report on membranous nephropathy: proposal for a novel classification

S Sethi, LH Beck Jr, RJ Glassock, M Haas… - Mayo Clinic …, 2023 - Elsevier
Membranous nephropathy (MN) is a pattern of injury caused by autoantibodies binding to
specific target antigens, with accumulation of immune complexes along the subepithelial …

[HTML][HTML] Perspectives in membranous nephropathy

NM Tomas, TB Huber, E Hoxha - Cell and Tissue Research, 2021 - Springer
The identification of the phospholipase A2 receptor 1 (PLA2R) and thrombospondin type-1
domain-containing protein 7A (THSD7A) as podocyte antigens in adult patients with …

[HTML][HTML] Primary membranous glomerulonephritis: the role of serum and urine biomarkers in patient management

SM Maifata, R Hod, F Zakaria, FA Ghani - Biomedicines, 2019 - mdpi.com
The detection of phospholipase A2 receptor (PLA2R) and thrombospondin domain
containing 7A THSD7A among primary membranous glomerulonephritis (MGN) patients …

Podocyte antigen staining to identify distinct phenotypes and outcomes in membranous nephropathy: a retrospective multicenter cohort study

N Hanset, S Aydin, N Demoulin, JP Cosyns… - American Journal of …, 2020 - Elsevier
Rationale & Objective Membranous nephropathy (MN) is characterized by the deposition of
immune complexes along glomerular basement membranes. M-Type phospholipase A 2 …

[PDF][PDF] Membranous nephropathy: current understanding in the light of new advances

H Özer, I Baloğlu, FC Fervenza… - Turkish Journal of …, 2023 - turkjnephrol.org
Membranous nephropathy is the most common cause of primary nephrotic syndrome in
adults. The most important mechanism in its pathogenesis is loss of immune tolerance. New …

[HTML][HTML] Autoantibodies in the diagnosis, monitoring, and treatment of membranous nephropathy

V Tesar, Z Hruskova - Frontiers in Immunology, 2021 - frontiersin.org
The discovery of anti-podocyte antibodies in primary membranous nephropathy (MN) has
revolutionized our approach toward the diagnosis and treatment of this disease. Evaluation …

Membranous nephropathy: new pathogenic mechanisms and their clinical implications

E Hoxha, L Reinhard, RAK Stahl - Nature Reviews Nephrology, 2022 - nature.com
Membranous nephropathy (MN) is characterized histomorphologically by the presence of
immune deposits in the subepithelial space of the glomerular filtration barrier; its clinical …

New insights into membranous glomerulonephritis: from bench to bedside

C Murtas, P Ravani, GM Ghiggeri - Nephrology Dialysis …, 2011 - academic.oup.com
Idiopathic membranous nephropathy (IMN) is responsible for most cases of nephrotic
syndrome in adults [1]. Although spontaneous remission may occur in some cases and …

[HTML][HTML] Role of phospholipase A2 receptor 1 antibody level at diagnosis for long-term renal outcome in membranous nephropathy

M Mahmud, HO Pinnschmidt, L Reinhard… - PLoS …, 2019 - journals.plos.org
Background Membranous nephropathy (MN) is an autoimmune disease induced by
circulating antibodies against the podocyte protein phospholipase A2 receptor 1 (PLA2R1 …