[HTML][HTML] Mechanisms of primary membranous nephropathy

Y Gu, H Xu, D Tang - Biomolecules, 2021 - mdpi.com
Membranous nephropathy (MN) is an autoimmune disease of the kidney glomerulus and
one of the leading causes of nephrotic syndrome. The disease exhibits heterogenous …

[HTML][HTML] A Comprehensive Phenotypic and Functional Immune Analysis Unravels Circulating Anti–Phospholipase A2 Receptor Antibody Secreting Cells in …

C Cantarelli, M Jarque, A Angeletti, J Manrique… - Kidney international …, 2020 - Elsevier
Introduction Primary membranous nephropathy (MN) is characterized by the presence of
antipodocyte antibodies, but studies describing phenotypic and functional abnormalities in …

[HTML][HTML] Circulating TNF receptors are significant prognostic biomarkers for idiopathic membranous nephropathy

SM Lee, SH Yang, R Cha, M Kim, JN An, JH Paik… - PloS one, 2014 - journals.plos.org
Idiopathic membranous nephropathy (iMN) is a common cause of nephrotic syndrome in
adults. A biomarker to accurately indicate the severity of iMN and predict long-term …

[HTML][HTML] How times have changed! A cornucopia of antigens for membranous nephropathy

TN Caza, LF Al-Rabadi, LH Beck Jr - Frontiers in Immunology, 2021 - frontiersin.org
The identification of the major target antigen phospholipase A2 receptor (PLA2R) in the
majority of primary (idiopathic) cases of membranous nephropathy (MN) has been followed …

Low-molecular-weight proteins as prognostic markers in idiopathic membranous nephropathy

JAJG van den Brand, JM Hofstra… - Clinical journal of the …, 2011 - journals.lww.com
Background Accurate prediction of prognosis in idiopathic membranous nephropathy (iMN)
allows restriction of immunosuppressive therapy to patients at high risk for ESRD. Here we …

Serine protease HTRA1 as a novel target antigen in primary membranous nephropathy

LF Al-Rabadi, T Caza, C Trivin-Avillach… - Journal of the …, 2021 - journals.lww.com
Background Identification of target antigens PLA2R, THSD7A, NELL1, or Semaphorin-3B
can explain the majority of cases of primary membranous nephropathy (MN). However …

[HTML][HTML] Recent advances in clinical diagnosis and pharmacotherapy options of membranous nephropathy

YN Wang, HY Feng, X Nie, YM Zhang, L Zou… - Frontiers in …, 2022 - frontiersin.org
Membranous nephropathy (MN) is the most common cause of nephrotic syndrome among
adults, which is the leading glomerular disease that recurs after kidney transplantation …

[HTML][HTML] A cohort study of membranous nephropathy, primary or secondary

M Arghiani, BH Zamani, F Nazemian, S Samadi… - BMC nephrology, 2021 - Springer
Abstract Background Although IgG4 deposit against phospholipase A2 receptor (anti-
PLA2R) is predominantly presented in the renal biopsy of patients with primary membranous …

Characterization of autoantibodies in primary membranous nephropathy and their clinical significance

RAK Stahl, L Reinhard, E Hoxha - Expert Review of Clinical …, 2019 - Taylor & Francis
Introduction: Membranous nephropathy (MN) is the most common cause of a nephrotic
syndrome in Caucasian adults. The identification of target antigens in MN in the last decade …

[HTML][HTML] Immunology of membranous nephropathy

S Akiyama, E Imai, S Maruyama - F1000Research, 2019 - ncbi.nlm.nih.gov
Accounting for about 20 to 50% of cases of primary nephrotic syndrome, membranous
nephropathy (MN) is the leading cause of nephrotic syndrome in adults. A rat model created …