Identification and characterization of a new autoimmune protein in membranous nephropathy by immunoscreening of a renal cDNA library

F Cavazzini, R Magistroni, L Furci, V Lupo, G Ligabue… - PloS one, 2012 - journals.plos.org
Membranous Nephropathy (MN) represents a large amount of Nephrotic Syndromes in the
adult population and its definitive diagnosis is currently carried out through biopsy. An …

Detection and monitoring PLA2R autoantibodies by LIPS in membranous nephropathy

PD Burbelo, LH Beck Jr, M Waldman - Journal of immunological methods, 2017 - Elsevier
Autoantibodies against the M-type phospholipase A 2 receptor (PLA 2 R) are specific
markers for primary membranous nephropathy (MN). Quantification of PLA 2 R …

Ultrasensitive quantitation of anti-phospholipase A2 receptor antibody as a diagnostic and prognostic indicator of idiopathic membranous nephropathy

Q Zhang, B Huang, X Liu, B Liu, Y Zhang, Z Zhang… - Scientific Reports, 2017 - nature.com
Anti-phospholipase A2 receptor antibody (PLA2R-Ab) is useful for affirming the diagnosis of
idiopathic membranous nephropathy (IMN). Time-resolved fluoroimmunoassay (TRFIA) is …

Discovery of seven novel putative antigens in membranous nephropathy and membranous lupus nephritis identified by mass spectrometry

TN Caza, AJ Storey, SI Hassen, C Herzog… - Kidney international, 2023 - Elsevier
Multiple autoantigens have been identified in membranous nephropathy (MN) by tissue-
based proteomics. However, antigenic targets of disease are unknown for over 10% of …

Anti-phospholipase A2 receptor antibodies directly induced podocyte damage in vitro

Y Li, J Yu, M Wang, Z Cui, M Zhao - Renal Failure, 2022 - Taylor & Francis
Background The pathogenesis of primary membranous nephropathy (MN) involves the
antibodies against antigens on the cell surface of podocytes, with the majority of M-type …

Renal outcomes of idiopathic and atypical membranous nephropathy in adult Chinese patients: a single center retrospective cohort study

Z Jiang, M Cai, B Dong, Y Yan, Y Wang, X Li, C Shao… - BMC nephrology, 2021 - Springer
Background Membranous nephropathy (MN) is mainly classified into idiopathic MN (iMN)
and secondary MN in etiology. In recent years, a new kind of membranous nephropathy …

[PDF][PDF] Complement pathways in membranous nephropathy: complex and multifactorial

V Brglez, S Boyer-Suavet, B Seitz-Polski - Kidney International Reports, 2020 - Elsevier
Membranous nephropathy (MN) is a rare, but severe autoimmune kidney disease and a
major cause of nephrotic syndrome in adults. Clinically defined by nephrotic syndrome …

[HTML][HTML] A review of the current practice of diagnosis and treatment of idiopathic membranous nephropathy in China

L Wu, J Lai, Y Ling, Y Weng, S Zhou, S Wu… - … Medical Journal of …, 2021 - ncbi.nlm.nih.gov
Idiopathic membranous nephropathy (IMN), a common pathological type of nephrotic
syndrome, is one of the main causes of kidney failure. With an increasing prevalence, IMN …

Serum anti-PLA2R antibody as a diagnostic biomarker of idiopathic membranous nephropathy: the optimal cut-off value for Chinese patients

Y Liu, X Li, C Ma, P Wang, J Liu, H Su, H Zhuo… - Clinica Chimica …, 2018 - Elsevier
Background The M-type phospholipase A2 receptor (PLA2R) is a specific target autoantigen
identified in idiopathic membranous nephropathy (IMN). The autoantibody against PLA2R …

Anti-PLA2R antibodies as a prognostic factor in PLA2R-related membranous nephropathy

SA Timmermans, MA Abdul Hamid… - American journal of …, 2015 - karger.com
Background: The natural course of idiopathic membranous nephropathy (MN) varies, as it is
known through favorable outcomes in most patients. However, one third of patients with …