An isotope-labeled chemical derivatization method for the quantitation of short-chain fatty acids in human feces by liquid chromatography–tandem mass spectrometry

J Han, K Lin, C Sequeira, CH Borchers - Analytica chimica acta, 2015 - Elsevier
Short-chain fatty acids (SCFAs) are produced by anaerobic gut microbiota in the large
bowel. Qualitative and quantitative measurements of SCFAs in the intestinal tract and the …

Quantification of fecal short chain fatty acids by liquid chromatography tandem mass spectrometry—investigation of pre-analytic stability

G Liebisch, J Ecker, S Roth, S Schweizer, V Öttl… - Biomolecules, 2019 - mdpi.com
Short chain fatty acids (SCFAs) are generated by the degradation and fermentation of
complex carbohydrates,(ie, dietary fiber) by the gut microbiota relevant for microbe–host …

A sensitive GC/MS detection method for analyzing microbial metabolites short chain fatty acids in fecal and serum samples

S Zhang, H Wang, MJ Zhu - Talanta, 2019 - Elsevier
Gut microbiota and their major metabolites, short-chain fatty acids (SCFAs), are recognized
as important players in gut homeostasis and metabolic disease occurance. A convenient …

Simultaneous quantification of straight-chain and branched-chain short chain fatty acids by gas chromatography mass spectrometry

L He, MAI Prodhan, F Yuan, X Yin… - … of Chromatography B, 2018 - Elsevier
Biomedical research in areas such as metabolic disorders, neuromodulatory, and
immunomodulatory conditions involves lipid metabolism and demands a reliable and …

Rapid profiling method for mammalian feces short chain fatty acids by GC-MS

T Furuhashi, K Sugitate, T Nakai, Y Jikumaru… - Analytical …, 2018 - Elsevier
Short chain fatty acids (SCFAs) are key feces metabolites generated by gut bacteria
fermentation. Despite the importance of profiling feces SCFAs, technical difficulties in …

Analysis of short-chain fatty acids in human feces: a scoping review

M Primec, D Mičetić-Turk, T Langerholc - Analytical biochemistry, 2017 - Elsevier
Short-chain fatty acids (SCFAs) play a crucial role in maintaining homeostasis in humans,
therefore the importance of a good and reliable SCFAs analytical detection has raised a lot …

Stable isotope labeling combined with liquid chromatography-tandem mass spectrometry for comprehensive analysis of short-chain fatty acids

J Zheng, SJ Zheng, WJ Cai, L Yu, BF Yuan… - Analytica Chimica Acta, 2019 - Elsevier
Short-chain fatty acids (SCFAs) are one class of bacterial metabolites mainly formed by gut
microbiota from undigested fibers and proteins. These molecules are able to mediate signal …

Determination of short-chain fatty acids in rat and human feces by high-performance liquid chromatography with electrochemical detection

A Kotani, Y Miyaguchi, M Kohama, T Ohtsuka… - Analytical sciences, 2009 - Springer
A simple method for determining short-chain fatty acids (SCFAs) in rat and human feces was
developed using high-performance liquid chromatography with electrochemical detection …

A novel LCMSMS method for quantitative measurement of short-chain fatty acids in human stool derivatized with 12C-and 13C-labelled aniline

JCY Chan, DYQ Kioh, GC Yap, BW Lee… - … of pharmaceutical and …, 2017 - Elsevier
A novel liquid chromatography tandem mass spectrometry (LCMSMS) method for the
quantitative measurement of gut microbial-derived short-chain fatty acids (SCFAs) in human …

Orthogonal Comparison of GC–MS and 1H NMR Spectroscopy for Short Chain Fatty Acid Quantitation

J Cai, J Zhang, Y Tian, L Zhang, E Hatzakis… - Analytical …, 2017 - ACS Publications
Short chain fatty acids (SCFAs) are important regulators of host physiology and metabolism
and may contribute to obesity and associated metabolic diseases. Interest in SCFAs has …