Elevated pretreatment serum concentration of YKL‐40—An independent prognostic biomarker for poor survival in patients with metastatic nonsmall cell lung cancer

I Thöm, B Andritzky, G Schuch, I Burkholder, L Edler… - Cancer, 2010 - Wiley Online Library
BACKGROUND: The glycoprotein YKL‐40 is synthesized both by cancer cells and by tumor‐
associated macrophages and plays a functional role in tumor progression. Consequently …

High serum levels of YKL‐40 in patients with squamous cell carcinoma of the head and neck are associated with short survival

A Roslind, JS Johansen, IJ Christensen… - … journal of cancer, 2008 - Wiley Online Library
YKL‐40 is a glycoprotein secreted by macrophages, neutrophils and malignant tumor cells.
Elevated serum levels of YKL‐40 are associated with poor prognosis in several …

Elevated serum level of YKL‐40 is an independent prognostic factor for poor survival in patients with metastatic melanoma

H Schmidt, JS Johansen, J Gehl… - … Journal of the …, 2006 - Wiley Online Library
BACKGROUND YKL‐40 is a growth factor for connective tissue cells and stimulates
migration of endothelial cells. Cancer cells, macrophages, and neutrophils secrete YKL‐40 …

[HTML][HTML] Serum YKL-40 level is associated with the chemotherapy response and prognosis of patients with small cell lung cancer

CH Xu, LK Yu, KK Hao - PLoS One, 2014 - journals.plos.org
This study was to explore the association between the serum YKL-40 level and the clinical
characteristics, the response to chemotherapy and prognosis in small cell lung cancer …

High serum YKL-40 level in patients with small cell lung cancer is related to early death

JS Johansen, L Drivsholm, PA Price, IJ Christensen - Lung cancer, 2004 - Elsevier
YKL-40, a growth factor for connective tissue cells, is secreted by cancer cells and
macrophages. Elevated serum YKL-40 in patients with metastatic carcinoma has been …

[HTML][HTML] High serum YKL-40 is a poor prognostic marker in patients with advanced non-small cell lung cancer

IK Choi, YH Kim, JS Kim, JH Seo - Acta Oncologica, 2010 - Taylor & Francis
Despite recent advances in the field of medical oncology, patients with advanced non-small
cell lung cancer (NSCLC) have a disappointing long-term prognosis. Accurate prognostic …

High serum YKL‐40 level after surgery for colorectal carcinoma is related to short survival

C Cintin, JS Johansen, IJ Christensen… - … Journal of the …, 2002 - Wiley Online Library
BACKGROUND YKL‐40 is a member of family 18 glycosyl hydrolases. YKL‐40 is a growth
factor and may stimulate migration of endothelial cells. YKL‐40 may also play a role in …

High serum concentration of YKL-40 is associated with short survival in patients with acute myeloid leukemia

OJ Bergmann, JS Johansen, TW Klausen… - Clinical Cancer …, 2005 - AACR
Purpose: YKL-40 is secreted by cancer cells, macrophages, and neutrophils. It may be a
growth or differentiation factor, play a role in angiogenesis, or protect against apoptosis …

[PDF][PDF] Serum YKL-40 predicts relapse-free and overall survival in patients with American Joint Committee on Cancer stage I and II melanoma

H Schmidt, JS Johansen, P Sjoegren… - Journal of Clinical …, 2006 - researchgate.net
Purpose To evaluate the novel tumor biomarker YKL-40 in serial serum samples from
patients with American Joint Committee on Cancer (AJCC) stage I and II melanoma from the …

Plasma YKL-40: a potential new cancer biomarker?

JS Johansen, NA Schultz, BV Jensen - Future Oncology, 2009 - Future Medicine
YKL-40, a 40-kDa secreted glycoprotein, with its gene located on chromosome 1q32. 1, is
produced by cancer cells and inflammatory cells and has a role in inflammation, cell …