Cadmium-induced testicular injury

ER Siu, DD Mruk, CS Porto, CY Cheng - Toxicology and applied …, 2009 - Elsevier
Cadmium (Cd) is an environmental toxicant and an endocrine disruptor in humans and
rodents. Several organs (eg, kidney, liver) are affected by Cd and recent studies have …

Cadmium as a testicular toxicant: A Review

JK Bhardwaj, H Panchal, P Saraf - Journal of Applied …, 2021 - Wiley Online Library
Cadmium (Cd) is a toxic heavy metal with no known biological functions in the human body.
Due to a considerably long biological half‐life and very low rate of excretion, accumulation …

Mechanisms of cadmium-induced testicular injury: a risk to male fertility

W Ali, Y Ma, J Zhu, H Zou, Z Liu - Cells, 2022 - mdpi.com
Cadmium is a heavy toxic metal with unknown biological functions in the human body. Over
time, cadmium accretion in the different visceral organs (liver, lungs, kidney, and testis) is …

Cadmium-induced activation of stress signaling pathways, disruption of ubiquitin-dependent protein degradation and apoptosis in primary rat Sertoli cell-gonocyte …

X Yu, S Hong, EM Faustman - Toxicological sciences, 2008 - academic.oup.com
Cadmium (Cd) is a ubiquitous environmental pollutant that has been associated with male
reproductive toxicity in both humans and animal models. The underlying mechanism of this …

The environment and male reproduction: The effect of cadmium exposure on reproductive function and its implication in fertility

C De Angelis, M Galdiero, C Pivonello, C Salzano… - Reproductive …, 2017 - Elsevier
Cadmium is an environmental pollutant known as endocrine disruptor. Testis is particularly
susceptible to cadmium, and testis injury occurs at high but even low levels of exposure …

Cadmium-induced damage to primary cultures of rat Leydig cells

JM Yang, M Arnush, QY Chen, XD Wu, B Pang… - Reproductive …, 2003 - Elsevier
The mechanism of testicular toxicity of cadmium is poorly understood. Previous studies
focusing on cadmium-related changes in testicular histopathology have implicated testicular …

Toxicological effects of cadmium on mammalian testis

Q Zhu, X Li, RS Ge - Frontiers in genetics, 2020 - frontiersin.org
Cadmium is a heavy metal, and people are exposed to it through contaminated foods and
smoking. In humans and other mammals, cadmium causes damage to male testis. In this …

[HTML][HTML] Exposure to low-dose cadmium induces testicular ferroptosis

L Xiong, B Zhou, JL Young, K Wintergerst… - … and environmental safety, 2022 - Elsevier
As an environmental pollutant, cadmium (Cd) has been widely reported to induce male
infertility due to its gonadotoxicity. However, the specific mechanism of Cd-induced testicular …

Subacute testicular toxicity to cadmium exposure intraperitoneally and orally

VGS Mouro, ALP Martins, J Silva… - Oxidative medicine …, 2019 - Wiley Online Library
The toxic effects of cadmium (Cd) on reproductive parameters are widely described in the
literature. Experimental models often make use of the intraperitoneal route (ip), although …

Environmental toxicants and male reproductive function

CY Cheng, EWP Wong, PPY Lie, MWM Li, L Su… - …, 2011 - Taylor & Francis
Environmental toxicants, such as cadmium and bisphenol A (BPA) are endocrine disruptors.
In utero, perinatal, or neonatal exposure of BPA to rats affect the male reproductive function …