Vaccination with Live Yersinia pestis Primes CD4 and CD8 T Cells That Synergistically Protect against Lethal Pulmonary Y. pestis Infection
AV Philipovskiy, ST Smiley - Infection and Immunity, 2007 - Am Soc Microbiol
Vaccination with live attenuated Yersinia pestis confers protection against pneumonic
plague but is not considered safe for general use. Subunit plague vaccines containing the Y …
plague but is not considered safe for general use. Subunit plague vaccines containing the Y …
Antibodies and cytokines independently protect against pneumonic plague
LW Kummer, FM Szaba, MA Parent, JJ Adamovicz… - Vaccine, 2008 - Elsevier
Yersinia pestis causes pneumonic plague, an exceptionally virulent disease for which we
lack a safe and effective vaccine. Antibodies specific for the Y. pestis F1 and LcrV proteins …
lack a safe and effective vaccine. Antibodies specific for the Y. pestis F1 and LcrV proteins …
Yersinia pestis V Protein Epitopes Recognized by CD4 T Cells
MA Parent, KN Berggren, IK Mullarky… - Infection and …, 2005 - Am Soc Microbiol
Pneumonic plague, an often-fatal disease for which no vaccine is presently available, results
from pulmonary infection by the bacterium Yersinia pestis. The Y. pestis V protein is a …
from pulmonary infection by the bacterium Yersinia pestis. The Y. pestis V protein is a …
Cell-Mediated Protection against Pulmonary Yersinia pestis Infection
MA Parent, KN Berggren, LW Kummer… - Infection and …, 2005 - Am Soc Microbiol
Pulmonary infection with the bacterium Yersinia pestis causes pneumonic plague, an often-
fatal disease for which no vaccine is presently available. Antibody-mediated humoral …
fatal disease for which no vaccine is presently available. Antibody-mediated humoral …
Yersinia pestis YopE contains a dominant CD8 T cell epitope that confers protection in a mouse model of pneumonic plague
JS Lin, FM Szaba, LW Kummer, BA Chromy… - The Journal of …, 2011 - journals.aai.org
Septic bacterial pneumonias are a major cause of death worldwide. Several of the highest
priority bioterror concerns, including anthrax, tularemia, and plague, are caused by bacteria …
priority bioterror concerns, including anthrax, tularemia, and plague, are caused by bacteria …
Cell-mediated defense against Yersinia pestis infection
ST Smiley - The Genus Yersinia: From Genomics to Function, 2007 - Springer
Yersinia pestis (Yp)-one of the world's most deadly human pathogens-is the gram-negative
bacterium that causes pneumonic plague. Virulent antibiotic-resistant Yp strains exist and …
bacterium that causes pneumonic plague. Virulent antibiotic-resistant Yp strains exist and …
Immune defense against pneumonic plague
ST Smiley - Immunological reviews, 2008 - Wiley Online Library
Yersinia pestis is one of the world's most virulent human pathogens. Inhalation of this Gram‐
negative bacterium causes pneumonic plague, a rapidly progressing and usually fatal …
negative bacterium causes pneumonic plague, a rapidly progressing and usually fatal …
Current challenges in the development of vaccines for pneumonic plague
ST Smiley - Expert review of vaccines, 2008 - Taylor & Francis
Inhalation of Yersinia pestis bacilli causes pneumonic plague, a rapidly progressing and
exceptionally virulent disease. Extensively antibiotic-resistant Y. pestis strains exist and we …
exceptionally virulent disease. Extensively antibiotic-resistant Y. pestis strains exist and we …
D27-pLpxL, an Avirulent Strain of Yersinia pestis, Primes T Cells That Protect against Pneumonic Plague
FM Szaba, LW Kummer, LB Wilhelm, JS Lin… - Infection and …, 2009 - Am Soc Microbiol
Vaccinating with live, conditionally attenuated, pigmentation (Pgm)-deficient Yersinia pestis
primes T cells that protect mice against pneumonic plague. However, Pgm-deficient strains …
primes T cells that protect mice against pneumonic plague. However, Pgm-deficient strains …
[HTML][HTML] TNFα and IFNγ but Not Perforin Are Critical for CD8 T Cell-Mediated Protection against Pulmonary Yersinia pestis Infection
FM Szaba, LW Kummer, DK Duso, EP Koroleva… - PLoS …, 2014 - journals.plos.org
Septic pneumonias resulting from bacterial infections of the lung are a leading cause of
human death worldwide. Little is known about the capacity of CD8 T cell-mediated immunity …
human death worldwide. Little is known about the capacity of CD8 T cell-mediated immunity …