ZEB1: at the crossroads of epithelial-mesenchymal transition, metastasis and therapy resistance
Zinc finger E-box binding homeobox 1 (ZEB1) is a transcription factor that promotes tumor
invasion and metastasis by inducing epithelial-mesenchymal transition (EMT) in carcinoma …
invasion and metastasis by inducing epithelial-mesenchymal transition (EMT) in carcinoma …
ZEB1: a critical regulator of cell plasticity, DNA damage response, and therapy resistance
The predominant way in which conventional chemotherapy kills rapidly proliferating cancer
cells is the induction of DNA damage. However, chemoresistance remains the main obstacle …
cells is the induction of DNA damage. However, chemoresistance remains the main obstacle …
The crucial role of ZEB2: from development to epithelial‐to‐mesenchymal transition and cancer complexity
Zinc finger E‐box binding homeobox 2 (ZEB2) is a DNA‐binding transcription factor, which
is mainly involved in epithelial‐to‐mesenchymal transition (EMT). EMT is a conserved …
is mainly involved in epithelial‐to‐mesenchymal transition (EMT). EMT is a conserved …
ZEB1 confers chemotherapeutic resistance to breast cancer by activating ATM
X Zhang, Z Zhang, Q Zhang, Q Zhang, P Sun… - Cell death & …, 2018 - nature.com
Although zinc finger E-box binding homeobox 1 (ZEB1) has been identified as a key factor in
the regulation of breast cancer differentiation and metastasis, its potential role in modulating …
the regulation of breast cancer differentiation and metastasis, its potential role in modulating …
Regulation of ZEB1 function and molecular associations in tumor progression and metastasis
M Perez-Oquendo, DL Gibbons - Cancers, 2022 - mdpi.com
Simple Summary Given the importance of the epithelial-to-mesenchymal transition in tumor
progression and the pivotal role of ZEB1 as a transcriptional repressor during this process …
progression and the pivotal role of ZEB1 as a transcriptional repressor during this process …
Pleiotropic roles for ZEB1 in cancer
J Caramel, M Ligier, A Puisieux - Cancer research, 2018 - AACR
ZEB1 is a prime element of a network of transcription factors that controls epithelial-to-
mesenchymal transition (EMT), a reversible embryonic transdifferentiation program that …
mesenchymal transition (EMT), a reversible embryonic transdifferentiation program that …
[HTML][HTML] ZEB1: catalyst of immune escape during tumor metastasis
J Lu, F Fei, C Wu, J Mei, J Xu, P Lu - Biomedicine & Pharmacotherapy, 2022 - Elsevier
The transcription factor zinc finger E-box binding homeobox 1 (ZEB1) is a critical inducer of
epithelial mesenchymal transformation (EMT) and plays a robust role in tumor metastasis. It …
epithelial mesenchymal transformation (EMT) and plays a robust role in tumor metastasis. It …
[HTML][HTML] The roles of ZEB1 in tumorigenic progression and epigenetic modifications
Y Zhang, L Xu, A Li, X Han - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Highly expressed Zinc-finger E-box binding protein 1 (ZEB1) is significantly associated with
the malignancy of various cancers. Signal transduction and activation of ZEB1 play …
the malignancy of various cancers. Signal transduction and activation of ZEB1 play …
The transcription factor ZEB1 is aberrantly expressed in aggressive uterine cancers
NS Spoelstra, NG Manning, Y Higashi, D Darling… - Cancer research, 2006 - AACR
The transcription factor ZEB1 (δEF1 in mice) has been implicated in cellular processes
during development and tumor progression including epithelial to mesenchymal transition …
during development and tumor progression including epithelial to mesenchymal transition …
Zeb1 links epithelial-mesenchymal transition and cellular senescence
Y Liu, S El-Naggar, DS Darling, Y Higashi, DC Dean - 2008 - journals.biologists.com
Overexpression of zinc finger E-box binding homeobox transcription factor 1 (Zeb1) in
cancer leads to epithelial-to-mesenchymal transition (EMT) and increased metastasis. As …
cancer leads to epithelial-to-mesenchymal transition (EMT) and increased metastasis. As …