Low levels of IgM antibodies to phosphorylcholine predict cardiovascular disease in 60-year old men: effects on uptake of oxidized LDL in macrophages as a potential …
U de Faire, J Su, X Hua, A Frostegård, M Halldin… - Journal of …, 2010 - Elsevier
OBJECTIVE: We here determine the role of IgM antibodies against phosphorylcholine (anti-
PC) in prediction of cardiovascular disease (CVD) and on macrophage uptake of Oxidized …
PC) in prediction of cardiovascular disease (CVD) and on macrophage uptake of Oxidized …
Low levels of IgM antibodies against phosphorylcholine predict development of acute myocardial infarction in a population-based cohort from northern Sweden
H Grönlund, G Hallmans, JH Jansson… - European Journal of …, 2009 - academic.oup.com
Objective Phosphorylcholine (PC) is one important epitope on oxidized low-density
lipoprotein that may play an important role by contributing to the atherogenicity of oxidized …
lipoprotein that may play an important role by contributing to the atherogenicity of oxidized …
Low level natural antibodies against phosphorylcholine: a novel risk marker and potential mechanism in atherosclerosis and cardiovascular disease
J Frostegård - Clinical immunology, 2010 - Elsevier
Atherosclerosis is an inflammatory condition characterised by an abundance of activated
immunocompetent cells in plaques which cause cardiovascular disease (CVD) when they …
immunocompetent cells in plaques which cause cardiovascular disease (CVD) when they …
Low levels of IgM antibodies against phosphorylcholine—a potential risk marker for ischemic stroke in men
BG Sjöberg, J Su, I Dahlbom, H Grönlund, M Wikström… - Atherosclerosis, 2009 - Elsevier
BACKGROUND: Natural antibodies specific for phosphorylcholine (anti-PC) have been
implicated as protective factors in atherosclerosis. We herein determined the relationship …
implicated as protective factors in atherosclerosis. We herein determined the relationship …
[HTML][HTML] IgM phosphorylcholine antibodies inhibit cell death and constitute a strong protection marker for atherosclerosis development, particularly in combination with …
R Fiskesund, J Su, I Bulatovic, M Vikström… - Results in …, 2012 - Elsevier
Background We have reported that anti-phosphorylcholine (anti-PC) IgM is a protection
marker for human cardiovascular disease (CVD) and atherosclerosis. We here investigate …
marker for human cardiovascular disease (CVD) and atherosclerosis. We here investigate …
Natural antibodies against phosphorylcholine in cardiovascular disease
U De Faire, J Frostegård - Annals of the New York Academy of …, 2009 - Wiley Online Library
Atherosclerosis is a chronic inflammatory disease characterized by the presence of activated
immune‐competent cells in the lesions, producing mainly proinflammatory cytokines …
immune‐competent cells in the lesions, producing mainly proinflammatory cytokines …
Antibodies of IgM subclass to phosphorylcholine and oxidized LDL are protective factors for atherosclerosis in patients with hypertension
J Su, A Georgiades, R Wu, T Thulin, U de Faire… - Atherosclerosis, 2006 - Elsevier
OBJECTIVE: To determine the importance of antibodies against phosphorylcholine (PC) and
oxidized low density lipoprotein (OxLDL) for development of atherosclerosis. METHODS …
oxidized low density lipoprotein (OxLDL) for development of atherosclerosis. METHODS …
Antibodies against phosphorylcholine and protection against atherosclerosis, cardiovascular disease and chronic inflammation
J Frostegård - Expert Review of Clinical Immunology, 2022 - Taylor & Francis
Introduction Chronic inflammatory diseases include cardiovascular disease (CVD),
atherosclerosis, rheumatic and autoimmune diseases, and others, constituting a large part of …
atherosclerosis, rheumatic and autoimmune diseases, and others, constituting a large part of …
Low levels of antibodies against phosphorylcholine predict development of stroke in a population-based study from northern Sweden
R Fiskesund, B Stegmayr, G Hallmans, M Vikström… - Stroke, 2010 - Am Heart Assoc
Background and Purpose—Natural immunoglobulin M antibodies specific for
phosphorylcholine (anti-PC) have been implicated in atherosclerosis. We have shown …
phosphorylcholine (anti-PC) have been implicated in atherosclerosis. We have shown …
Atheroprotective natural anti-phosphorylcholine antibodies of IgM subclass are decreased in Swedish controls as compared to non-westernized individuals from New …
J Frostegård, WJ Tao, A Georgiades, L Råstam… - Nutrition & …, 2007 - Springer
Objective To determine the importance of IgM antibodies against phosphorylcholine (aPC),
a novel protective factor for cardiovascular disease (CVD), in a population with a non …
a novel protective factor for cardiovascular disease (CVD), in a population with a non …
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