Background Obtaining the necessary approvals and permission for clinical research
requires successful negotiation of the ethical and R&D layers of the NHS. Differences in …

Competition for clinical trial projects outsourced by the global pharmaceutical industry is
increasing with more countries bidding to provide these services. A comprehensive review …

Abstract The Clinical Trials Transformation Initiative (CTTI) Strengthening the Investigator
Community Project was prompted by the need to understand the reasons for high rates of …

Background The DAMOCLES project established a widely used Data Monitoring Committee
(DMC) Charter for randomised controlled trials (RCTs). Typically, within the UK, the DMC is …

The article discusses the recruitment and retention strategies being employed by the
contract research organization (CRO) industry. Topics include the skills analysis done by …

The DAMOCLES project established a Data Monitoring Committee Charter which has been
widely used for randomised controlled trials since 2005. As established within DAMOCLES …

As a community of investigators, we have struggled to improve the recruitment of
representative populations into heart failure (HF) trials. Emerging observations suggest we …

Over the past two decades, the number of clinical trials conducted globally has increased
thereby increasing demand for nurses working as Clinical Trial Nurses (CTNs), sometimes …

Objective To explore stakeholder perspectives upon participant retention in clinical trials,
and to generate strategies to support retention in a surgical, clinical trial. Study design and …

Background Participant recruitment in clinical trials is often challenging. Building
partnerships with healthcare organizations during proposal development facilitates access …