Objectives This study aimed to evaluate berberine (BBR) effects on myocardial hypertrophy
(MH) and associated mechanisms. Methods BBR effects on MH were evaluated in rats with …

Cardiac hypertrophy is a maladaptive change in response to pressure overload, and is also
an important risk for developing heart failure. Berberine is known to have cardioprotective …

Purpose Berberine was reported to exert beneficial effects on cardiac hypertrophy. However,
its cellular and molecular mechanisms still remained unclear. Methods Cardiac hypertrophy …

The present study aimed to test the hypothesis that berberine, a plant‐derived anti‐oxidant,
attenuates adverse left ventricular remodelling and improves cardiac function in a rat model …

Background Berberine has been verified to protect the heart from ischemia/reperfusion
injury through animal experiments. However, the cardioprotective properties of berberine …

Abstract Ischemia/reperfusion (I/R)-induced autophagy increases the severity of
cardiomyocyte injury. The aim of this study was to investigate the effects of berberine, a …

Alarin could alleviate myocardial infarction-induced heart failure. The present study was to
explore whether alarin could alleviate myocardial hypertrophy via inhibiting cyclic …

Aims Myocardial ischaemia/reperfusion injury (MIRI) is a major cause of heart failure after
myocardial infarction. Berberine (BBR) presents anti‐inflammatory and immunosuppressive …

Syringin, extracted from Eleutherococcus senticosus, is a major biologically active
component of Chinese herbs. Studies have certified the multiple pharmacological properties …

Several studies have shown that berberine (BBR) is effective in protecting against
myocardial ischemia‑reperfusion injury (MI/RI). However, the precise molecular mechanism …