TRPM4 channels in smooth muscle function

S Earley - Pflügers Archiv-European Journal of Physiology, 2013 - Springer
The melastatin (M) transient receptor potential (TRP) channel TRPM4 is selective for
monovalent cations and is activated by high levels of intracellular Ca 2+. TRPM4 is broadly …

Enhanced β-adrenergic cardiac reserve in Trpm4−/− mice with ischaemic heart failure

G Jacobs, W Oosterlinck, T Dresselaers… - Cardiovascular …, 2015 - academic.oup.com
Aims Heart failure (HF) is a complex syndrome characterized by critically reduced cardiac
contractility and function. We have shown previously that Transient Receptor Potential …

Tissue distribution profiles of the human TRPM cation channel family

E Fonfria, PR Murdock, FS Cusdin… - Journal of Receptors …, 2006 - Taylor & Francis
Eight members of the TRP-melastatin (TRPM) subfamily have been identified, whose
physiological functions and distribution are poorly characterized. Although tissue expression …

Silencing TRPM7 promotes growth/proliferation and nitric oxide production of vascular endothelial cells via the ERK pathway

K Inoue, ZG Xiong - Cardiovascular research, 2009 - academic.oup.com
Aims The presence and potential function of transient receptor potential melastatin 7
(TRPM7), a Ca2+-permeable non-selective cation channel of the TRP channel superfamily …

TRPM channels in the vasculature

A Zholos, C Johnson, T Burdyga… - Transient Receptor …, 2011 - Springer
Recent studies show that mammalian melastatin TRPM nonselective cation channels
(TRPM1-8), members of the largest and most diverse TRP subfamily, are widely expressed …

The role of the N terminus and transmembrane domain of TRPM8 in channel localization and tetramerization

CB Phelps, R Gaudet - Journal of Biological Chemistry, 2007 - ASBMB
Transient receptor potential (TRP) channels are a family of cation channels involved in
diverse cellular functions. They are composed of a transmembrane domain of six putative …

The different roles of the channel-kinases TRPM6 and TRPM7

D Cabezas-Bratesco, S Brauchi… - Current medicinal …, 2015 - ingentaconnect.com
Melastatin-related Transient Receptor Potential 6 and 7 (TRPM6 and TRPM7) are cation
channels with the almost unique trait of each possessing a kinase domain in its C terminus …

EB1‐and EB2‐dependent anterograde trafficking of TRPM4 regulates focal adhesion turnover and cell invasion

C Blanco, D Morales, I Mogollones… - The FASEB …, 2019 - Wiley Online Library
Transient receptor potential melastatin 4 (TRPM4) is a Ca2+‐activated nonselective cationic
channel involved in a wide variety of physiologic and pathophysiological processes …

Two decades of evolution of our understanding of the transient receptor potential melastatin 2 (TRPM2) cation channel

A Szollosi - Life, 2021 - mdpi.com
The transient receptor potential melastatin (TRPM) family belongs to the superfamily of TRP
ion channels. It consists of eight family members that are involved in a plethora of cellular …

[HTML][HTML] A structural overview of the ion channels of the TRPM family

Y Huang, R Fliegert, AH Guse, W Lü, J Du - Cell Calcium, 2020 - Elsevier
The TRPM (transient receptor potential melastatin) family belongs to the superfamily of TRP
cation channels. The TRPM subfamily is composed of eight members that are involved in …