Age-related macular degeneration: A two-level model hypothesis

MP Rozing, JA Durhuus, MK Nielsen, Y Subhi… - Progress in retinal and …, 2020 - Elsevier
Age-related diseases, including age-related macular degeneration (AMD), are of growing
importance in a world where population ageing has become a dominant global trend …

[HTML][HTML] Prediction model for prevalence and incidence of advanced age-related macular degeneration based on genetic, demographic, and environmental variables

JM Seddon, R Reynolds, J Maller… - … & visual science, 2009 - arvojournals.org
purpose. The joint effects of genetic, ocular, and environmental variables were evaluated
and predictive models for prevalence and incidence of AMD were assessed. methods …

Genetics of age-related macular degeneration: current concepts, future directions

MM DeAngelis, AC Silveira, EA Carr… - Seminars in …, 2011 - Taylor & Francis
Age-related macular degeneration (AMD) is a progressive degenerative disease which
leads to blindness, affecting the quality of life of millions of Americans. More than 1.75 …

Current concepts in the pathogenesis of age-related macular degeneration

MA Zarbin - Archives of ophthalmology, 2004 - jamanetwork.com
Objective To review and synthesize information concerning the pathogenesis ofage-related
macular degeneration (AMD). Methods Review of the English-language literature. Results …

Metabolomics in age-related macular degeneration: a systematic review

XW Hou, Y Wang, CW Pan - Investigative ophthalmology & …, 2020 - iovs.arvojournals.org
Purpose: Age-related macular degeneration (AMD) is one of the leading causes of
blindness among the elderly, and the exact pathogenesis of the AMD remains unclear. The …

Age-related macular degeneration: genetics and biology coming together

LG Fritsche, RN Fariss, D Stambolian… - Annual review of …, 2014 - annualreviews.org
Genetic and genomic studies have enhanced our understanding of complex
neurodegenerative diseases that exert a devastating impact on individuals and society. One …

Age-related macular degeneration (AMD): Alzheimer's disease in the eye?

K Kaarniranta, A Salminen… - Journal of …, 2011 - content.iospress.com
Age-related macular degeneration (AMD) is a late-onset, neurodegenerative retinal disease
that shares several clinical and pathological features with Alzheimer's disease (AD) …

[HTML][HTML] Oxidative stress, innate immunity, and age-related macular degeneration

PX Shaw, T Stiles, C Douglas, D Ho, W Fan… - AIMS molecular …, 2016 - ncbi.nlm.nih.gov
Age-related macular degeneration (AMD) is a leading cause of vision loss affecting tens of
millions of elderly worldwide. Early AMD is characterized by the appearance of soft drusen …

Risk factors for age-related macular degeneration

JR Evans - Progress in retinal and eye research, 2001 - Elsevier
There is an increasing body of evidence as to the risk factors for age-related macular
degeneration. Age and genetic make-up are the most important risk factors identified to date …

Unraveling a multifactorial late-onset disease: from genetic susceptibility to disease mechanisms for age-related macular degeneration

A Swaroop, EY Chew, C Bowes Rickman… - Annual review of …, 2009 - annualreviews.org
Aging-associated neurodegenerative diseases significantly influence the quality of life of
affected individuals. Genetic approaches, combined with genomic technology, have …