Background Acetaminophen (APAP) is a worldwide antipyretic as well as an analgesic
medication. It has been extensively utilized during the outbreak of coronavirus 2019 (COVID …

Tannic acid (TA) is the polyphenol that has beneficial health effects against oxidative stress.
However, the hepatoprotective effects of TA are still relatively unknown. In the present study …

Purposes Hepatic bioactivation of fluoxetine (FXN) could increase free radicals' generation
provoking hepatotoxicity. Therefore, the protective effects of ellagic acid (EA) and taurine …

Scope Existing research suggests that (−)‐epigallocatechin‐3‐gallate (EGCG), which is a
natural tea catechin active substance, can protect against liver injury. However, its …

Background Acetaminophen (paracetamol, APAP) overdose is the principal cause of acute
liver injury (ALI) that leads to liver failure typified with oxidative stress, mitochondrial and …

The endoplasmic reticulum (ER) controls many biological functions besides maintaining the
function of liver cells. Various studies reported the role of the ER stress and UPR signaling …

Ethanol (EtOH) is most widely used in alcoholic beverages to prepare alcohol. As EtOH is
mainly metabolised in the liver, the excessive consumption of EtOH forms a primary toxic …

Background of the study: Hepatic encephalopathy (HE) is a complication in which brain
ammonia (NH 4+) levels reach critically high concentrations because of liver failure. HE …

Cyclophosphamide (CP) is widely used as an immunosuppressive and chemotherapeutic
drug. However, its therapeutic application is restricted by its adverse effects, particularly …

Phytochemical investigation of the butanol fraction (BUF) derived from the 70% aqueous
methanolic leaf extract of Barnebydendron riedelii led to the isolation of three flavonoid …