Monosodium glutamate (MSG), a commonly used flavor enhancer, has been reported to
induce hepatic and renal dysfunctions. In this study, the palliative role of protocatechuic acid …

Alcoholic abuse is one of the most serious causes of liver diseases worldwide. Although
detailed molecular pathogenesis of alcohol-induced liver damages remains elusive with …

Acetaminophen (APAP) is used as a primary drug due to its antipyretic and analgesic
activity. The mechanism of action of APAP toxicity in the liver is due to the depletion of …

This study was designed to evaluate the hepato and neuroprotective activity of Daflon and
low-dose γ radiation on thioacetamide (TAA)-induced liver damage and hepatic …

Hepatic encephalopathy (HE) is a prevalent complication of the central nervous system
(CNS) that is caused by acute or chronic liver failure. This study was designed to evaluate …

Cyclophosphamide (CP) is a widely used chemotherapeutic agent; however, its clinical
application is limited because of its multi-organ toxicity. Galangin (Gal) is a bioactive …

Hepatic encephalopathy (HE) is a severe neuropsychiatric complication due to acute or
chronic liver failure. In this work, an acute thioacetamide induced HE mice model was …

Overuse of therapeutic drugs such as acetaminophen often affects liver, and may lead to
inflammatory mediated liver cell death. Here, we studied the effect of Terminalia arjuna (TA) …

AIM: To propose an alternative model of hepatic encephalopathy (HE) in mice, resembling
the human features of the disease. METHODS: Mice received two consecutive …

Overdose of acetaminophen (APAP) is a common cause of acute liver failure. Oxidative
stress and mitochondrial dysfunction are related to APAP-induced hepatotoxicity. This study …