Manipulations of the sleep-wake cycle, whether of duration (total or partial sleep deprivation
[SD]) or timing (partial SD, phase advance), have profound and rapid effects on depressed …

Depression is increasingly prevalent in Western countries. It has severe consequences and
is associated with increased rates of disability, morbidity, and mortality. Despite numerous …

Chronic insomnia is a risk factor for the development of psychiatric disorders, including
depression, as well as a prodrome of major depressive episodes, a consequence or …

Sleep deprivation (SD) is a powerful antidepressant treatment that shows antidepressant
responses within hours in 40–60% of depressed patients. In more than 80% of responders …

Diurnal variation of depressive symptoms appears to be part of the core of depression. Yet
longitudinal investigation of an individual's pattern regularity, relation to clinical state, and …

It has been established that 4.4 to 20% of the general population suffers from a major
depressive disorder (MDD), which is frequently associated with a dysregulation of normal …

Objective: Disturbed sleep is typical for most depressed patients and complaints about
disordered sleep are the hallmarks of the disorder. Polysomnographic sleep research has …

This review examines the relationship between sleep and depression. Most depressive
disorders are characterized by subjective sleep disturbances, and the regulation of sleep is …

It is well established that sleep patterns are altered in psychiatric disorders and represent a
very common presenting complaint. Even though sleep disturbance is often a key feature of …

Sleep in depression exhibits pathognomonic changes which include a prolonged sleep
latency, a shallow fragmented sleep process, and precocious awakening in the morning …