Potential modulatory microbiome therapies for prevention or treatment of inflammatory bowel diseases

DV Bunt, AJ Minnaard, S El Aidy - Pharmaceuticals, 2021 - mdpi.com
A disturbed interaction between the gut microbiota and the mucosal immune system plays a
pivotal role in the development of inflammatory bowel disease (IBD). Various compounds …

Gut Microbiota Metabolites: Unveiling Their Role in Inflammatory Bowel Diseases and Fibrosis

F Bernardi, F D'Amico, S Bencardino, I Faggiani… - Pharmaceuticals, 2024 - mdpi.com
In recent years, there has been a growing focus on the intricate interplay between the gut
microbiota and host health, specifically in the context of inflammatory bowel diseases (IBDs) …

Gut microbiota-derived metabolites as key actors in inflammatory bowel disease

A Lavelle, H Sokol - Nature reviews Gastroenterology & hepatology, 2020 - nature.com
A key role of the gut microbiota in the establishment and maintenance of health, as well as in
the pathogenesis of disease, has been identified over the past two decades. One of the …

Diet–Microbiota Interplay: An Emerging Player in Macrophage Plasticity and Intestinal Health

C O'Mahony, A Amamou, S Ghosh - International Journal of Molecular …, 2022 - mdpi.com
Inflammatory bowel diseases (IBD) are chronic disorders of the gastrointestinal tract with an
increasing prevalence worldwide. Targeted therapies for IBD are limited by several factors …

Disturbances of the gut microbiota and microbiota-derived metabolites in inflammatory bowel disease

Y Hu, Z Chen, C Xu, S Kan, D Chen - Nutrients, 2022 - mdpi.com
Inflammatory bowel disease (IBD), comprising Crohn's disease (CD) and ulcerative colitis
(UC), is characterized as a chronic and recurrent inflammatory disease whose pathogenesis …

[HTML][HTML] Nutritional protective mechanisms against gut inflammation

M Viladomiu, R Hontecillas, L Yuan, P Lu… - The Journal of nutritional …, 2013 - Elsevier
Inflammatory bowel disease (IBD) is a debilitating and widespread immune-mediated illness
characterized by excessive inflammatory and effector mucosal responses leading to tissue …

Postbiotics: An alternative and innovative intervention for the therapy of inflammatory bowel disease

H Om, U Chand, PK Kushawaha - Microbiological Research, 2023 - Elsevier
Abstract Inflammatory Bowel Disease (IBD) is a persistent gastrointestinal (GI) tract
inflammatory disease characterized by downregulated mucosal immune activities and a …

Inflammatory bowel diseases: the role of gut microbiota

C De Musis, L Granata, M Dallio… - Current …, 2020 - ingentaconnect.com
Inflammatory bowel diseases (IBD) are chronic multifactorial diseases characterized by
partially unclear pathogenic mechanisms including changes in intestinal microbiota. Despite …

Dysbiotic gut microbiota-derived metabolites and their role in non-communicable diseases

J Tan, J Taitz, R Nanan, G Grau, L Macia - International Journal of …, 2023 - mdpi.com
Dysbiosis, generally defined as the disruption to gut microbiota composition or function, is
observed in most diseases, including allergies, cancer, metabolic diseases, neurological …

Recent advances in gut microbiota mediated therapeutic targets in inflammatory bowel diseases: emerging modalities for future pharmacological implications

M Shamoon, NM Martin, CL O'Brien - Pharmacological Research, 2019 - Elsevier
The inflammatory bowel diseases (IBDs) are chronic inflammatory conditions, which are
increasing in prevalence worldwide. The IBDs are thought to result from an aberrant immune …