[PDF][PDF] Hepatitis B virus replication in diverse cell types during chronic hepatitis B virus infection

A Mason, M Wick, H White, R Perrillo - Hepatology, 1993 - Wiley Online Library
Hepatitis B virus–specific nucleic acid sequences and proteins have been detected in
extrahepatic tissues of acutely and chronically infected patients. However, apart from …

Different forms of hepatitis B virus DNA and expression of HBV antigens in peripheral blood mononuclear cells in chronic hepatitis B

P Bouffard, JP Lamelin, F Zoulim… - Journal of medical …, 1990 - Wiley Online Library
The presence of both hepatitis B virus (HBV) DNA and HBV antigens (HBsAg, HBeAg) was
assessed in peripheral blood mononuclear cells (PBMC) from 32 patients chronically …

Transcription of hepatitis B virus in peripheral blood mononuclear cells from persistently infected patients

S Stoll-Becker, R Repp, D Glebe, S Schaefer… - Journal of …, 1997 - Am Soc Microbiol
Hepatitis B virus (HBV) has been reported to exist in peripheral blood mononuclear cells
(PBMC), but it is not clear whether it replicates there. A precondition for replication should be …

Correlation between liver histology and markers of hepatitis B virus replication in infected patients: a study by in situ hybridization

CJ Burrell, EJ Gowans, R Rowland, P Hall… - Hepatology, 1984 - journals.lww.com
Liver sections from 18 patients positive for hepatitis B surface antigen (HBsAg), and from 12
negative patients, were examined for the presence of hepatitis B virus (HBV) DNA using an …

Hepatitis B virus DNA in mononuclear cells and analysis of cell subsets for the presence of replicative intermediates of viral DNA

B Yoffe, CA Noonan, JL Melnick… - Journal of Infectious …, 1986 - academic.oup.com
To determine whether peripheral blood mononuclear cells (PBMCs) contain replicating
forms of hepatitis B virus (HBV) DNA and to define which cell subset may be permissive for …

[PDF][PDF] Hepatitis B virus DNA in peripheral‐blood mononuclear cells in chronic hepatitis B after HBsAg clearance

A Mason, B Yoffe, C Noonan, M Mearns… - …, 1992 - Wiley Online Library
In this study, peripheral‐blood mononuclear cells from patients with chronic hepatitis B and
spontaneous or therapy‐induced disappearance of HBsAg were examined for HBV DNA …

Extrahepatic hepatitis B virus DNA sequences in patients with acute hepatitis B infection

B Yoffe, DK Burns, HS Bhatt, B Combes - Hepatology, 1990 - journals.lww.com
Recent studies have demonstrated the presence of hepadnavirus–related nucleic acids in
extrahepatic tissues in various animal models. The prevalence and biological significance of …

In vitro experimental infection of primary human hepatocytes with hepatitis B virus

PR Galle, J Hagelstein, B Kommerell, M Volkmann… - Gastroenterology, 1994 - Elsevier
Abstract Background/Aims: Studies on the interaction of hepatitis B virus (HBV) with its host
cell require a suitable tissue culture system. This study used primary adult hepatocytes from …

Hepatitis B virus infection of adult human hepatocytes cultured in the presence of dimethyl sulfoxide

P Gripon, C Diot, N Theze, I Fourel, O Loreal… - Journal of …, 1988 - Am Soc Microbiol
We investigated the possibility of infecting normal adult human hepatocytes maintained in
pure cultures or in cocultures with hepatitis B virus (HBV). Several assays with different …

Effect of hepatocyte proliferation and cellular DNA synthesis on hepatitis B virus replication

A Ozer, VI Khaoustov, M Mearns, DE Lewis, RM Genta… - Gastroenterology, 1996 - Elsevier
BACKGROUND & AIMS: Interrelationship between hepatitis B virus (HBV) replication and
the stage of hepatocyte proliferation and differentiation may play an important role in the …