Valganciclovir

M Curran, S Noble - Drugs, 2001 - Springer
Abstract▴ Valganciclovir is a prodrug of ganciclovir which has been developed for the
treatment of cytomegalovirus (CMV) retinitis in patients with AIDS.▴ Oral valganciclovir is …

[HTML][HTML] Valganciclovir: a review of its use in the management of CMV infection and disease in immunocompromised patients

RS Cvetkovic, K Wellington - Drugs, 2005 - Springer
Valganciclovir (Valcyte™) is an orally administered prodrug of the standard anti-
cytomegalovirus (CMV) drug ganciclovir. Valganciclovir is as effective as intravenous …

Valganciclovir: a new oral alternative for cytomegalovirus retinitis in human immunodeficiency virus‐seropositive individuals

M Segarra‐Newnham… - … : The Journal of Human …, 2002 - Wiley Online Library
Oral valganciclovir recently was approved by the Food and Drug Administration for treatment
of cytomegalovirus (CMV) retinitis. We performed MEDLINE (June 1998–May 2002) and …

Pharmacokinetics of valganciclovir and ganciclovir following multiple oral dosages of valganciclovir in HIV-and CMV-seropositive volunteers

F Brown, L Banken, K Saywell, I Arum - Clinical pharmacokinetics, 1999 - Springer
Objective Ganciclovir is commonly used in the treatment of cytomegalovirus (CMV) disease
in patients who are immunocompromised and for the prevention of CMV disease in solid …

Valganciclovir in the treatment of cytomegalovirus retinitis in HIV-infected patients

AJ Patil, A Sharma, MC Kenney… - Clinical …, 2010 - Taylor & Francis
Oral valganciclovir is a new and highly efficacious alternative to the chronic administration of
ganciclovir in the treatment of cytomegalovirus (CMV) retinitis in HIV-infected patients. In …

Valganciclovir: an advance in cytomegalovirus therapeutics

JM Cocohoba, IR McNicholl - Annals of Pharmacotherapy, 2002 - journals.sagepub.com
OBJECTIVE: To review the pharmacology, pharmacokinetics, and preliminary clinical data
for valganciclovir, a new oral agent for the therapy of cytomegalovirus (CMV) retinitis. DATA …

A safety study of oral valganciclovir maintenance treatment of cytomegalovirus retinitis

J Lalezari, J Lindley, S Walmsley… - JAIDS Journal of …, 2002 - journals.lww.com
Valganciclovir, an oral prodrug of the anti-cytomegalovirus (CMV) agent ganciclovir, was
evaluated in a single-arm open-label safety study. AIDS patients (median CD4 lymphocyte …

[HTML][HTML] A controlled trial of valganciclovir as induction therapy for cytomegalovirus retinitis

DF Martin, J Sierra-Madero, S Walmsley… - … England Journal of …, 2002 - Mass Medical Soc
Background Valganciclovir is an orally administered prodrug that is rapidly hydrolyzed to
ganciclovir. We compared the effects of oral valganciclovir with those of intravenous …

Pharmacokinetic, safety, and antiviral profiles of oral ganciclovir in persons infected with human immunodeficiency virus: a phase I/II study

SA Spector, DF Busch, S Follansbee… - Journal of Infectious …, 1995 - academic.oup.com
Abstract A phase I/II study evaluated the pharmacokinetics, tolerability, and antiviral activity
of oral ganciclovir in persons infected with human immunodeficiency virus (HIV). Oral …

Ganciclovir absolute bioavailability and steady-state pharmacokinetics after oral administration of two 3000-mg/d dosing regimens in human immunodeficiency virus …

RD Anderson, KG Griffy, D Jung, A Door, JD Hulse… - Clinical …, 1995 - Elsevier
Oral ganciclovir has recently been approved for use in long-term maintenance therapy in the
treatment of cytomegalovirus (CMV) retinitis in immunocompromised patients. Although oral …