Novel therapeutic agents for the treatment of gastroenteropancreatic neuroendocrine tumors

ME Pavel, B Wiedenmann - Hormone and metabolic research, 2011 - thieme-connect.com
Neuroendocrine tumors (NET) are frequently diagnosed late and not amenable to curative
surgery due to metastatic disease to the liver and lymph nodes. The disease is complex and …

The emerging role of targeted therapies for advanced well-differentiated gastroenteropancreatic neuroendocrine tumors

JM Cloyd, B Konda, MH Shah… - Expert Review of Clinical …, 2019 - Taylor & Francis
Introduction: Gastroenteropancreatic (GEP) neuroendocrine tumors (NETs) are unique and
complex neoplasms, exhibiting a wide spectrum of diverse clinical behaviors. The …

[HTML][HTML] Current status and perspectives of targeted therapy in well-differentiated neuroendocrine tumors

BG Naraev, JR Strosberg, TR Halfdanarson - Oncology, 2012 - karger.com
Although neuroendocrine tumors (NET) are a relatively rare malignancy, the reported
incidence is increasing, and some of the current treatment options are limited in their …

Current clinical trials of targeted agents for well-differentiated neuroendocrine tumors

N Raj, D Reidy-Lagunes - Pancreas, 2014 - journals.lww.com
Neuroendocrine tumors (NETs) are a group of tumors originating in various locations,
including the gastrointestinal tract, lung, and pancreas. Clinical trial design and disease …

Gastroenteropancreatic neuroendocrine tumors

M Cives, JR Strosberg - CA: a cancer journal for clinicians, 2018 - Wiley Online Library
Neuroendocrine tumors (NETs) are heterogeneous malignancies arising from the diffuse
neuroendocrine system. They frequently originate in the gastroenteropancreatic (GEP) tract …

A review of systemic and liver-directed therapies for metastatic neuroendocrine tumors of the gastroenteropancreatic tract

JR Strosberg, A Cheema, LK Kvols - Cancer Control, 2011 - journals.sagepub.com
Background Treatment options for metastatic gastroenteropancreatic neuroendocrine
tumors (NETs) have evolved in recent years. The somatostatin analogs octreotide and …

Advances in the treatment of gastroenteropancreatic neuroendocrine tumors

PL Kunz, GA Fisher - Clinical and experimental gastroenterology, 2010 - Taylor & Francis
Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are a rare and heterogeneous
class of neoplasms. While surgical resection is the mainstay of treatment, non-surgical …

[HTML][HTML] New therapeutic approaches to metastatic gastroenteropancreatic neuroendocrine tumors: A glimpse into the future

EU Cidon - World journal of gastrointestinal oncology, 2017 - ncbi.nlm.nih.gov
Neuroendocrine (NE) gastroenteropancreatic tumors are a heterogeneous group of
neoplasias arising from neuroendocrine cells of the embryological gut. Their incidence have …

Medical treatment of gastroenteropancreatic neuroendocrine tumors

A Rinke, P Michl, T Gress - Cancers, 2012 - mdpi.com
Treatment of the clinically and prognostically heterogeneous neuroendocrine neoplasms
(NEN) should be based on a multidisciplinary approach, including surgical, interventional …

The evolving landscape of neuroendocrine tumors

EK Bergsland - Seminars in Oncology, 2013 - Elsevier
Neuroendocrine tumors (NET) encompass a heterogeneous group of tumors demonstrating
varied clinical behavior. The field has recently witnessed several important developments …