[HTML][HTML] An integrated computational-experimental approach reveals Yersinia pestis genes essential across a narrow or a broad range of environmental conditions

NJ Senior, K Sasidharan, RJ Saint, AE Scott… - BMC microbiology, 2017 - Springer
Abstract Background The World Health Organization has categorized plague as a re-
emerging disease and the potential for Yersinia pestis to also be used as a bioweapon …

Virulence genes regulated at the transcriptional level by Ca2+ in Yersinia pestis include structural genes for outer membrane proteins

SC Straley, WS Bowmer - Infection and immunity, 1986 - Am Soc Microbiol
Yersinia pestis, the causative agent of plague, has a virulence determinant called the low-
Ca2+ response (Lcr+ phenotype) that confers on the bacterium Ca2+ dependence for …

Yersinia pestis pH 6 antigen: genetic, biochemical, and virulence characterization of a protein involved in the pathogenesis of bubonic plague

LE Lindler, MS Klempner, SC Straley - Infection and immunity, 1990 - Am Soc Microbiol
We studied a protein antigen, designated pH 6 Ag, that has the same regulation of
expression as the previously described Yersinia pestis pH 6 Ag. Monospecific antiserum to …

Absence of Inflammation and Pneumonia during Infection with Nonpigmented Yersinia pestis Reveals a New Role for the pgm Locus in Pathogenesis

H Lee-Lewis, DM Anderson - Infection and immunity, 2010 - Am Soc Microbiol
Yersinia pestis causes primary pneumonic plague in many mammalian species, including
humans, mice, and rats. Virulent Y. pestis strains undergo frequent spontaneous deletion of …

Proteomic characterization of host response to Yersinia pestis and near neighbors

BA Chromy, J Perkins, JL Heidbrink… - Biochemical and …, 2004 - Elsevier
Host–pathogen interactions result in protein expression changes within both the host and
the pathogen. Here, results from proteomic characterization of host response following …

[HTML][HTML] Bacteriophage-Resistant Mutants in Yersinia pestis: Identification of Phage Receptors and Attenuation for Mice

AA Filippov, KV Sergueev, Y He, XZ Huang, BT Gnade… - PloS one, 2011 - journals.plos.org
Background Bacteriophages specific for Yersinia pestis are routinely used for plague
diagnostics and could be an alternative to antibiotics in case of drug-resistant plague. A …

Structural Organization of Virulence-Associated Plasmids of Yersinia pestis

P Hu, J Elliott, P McCready, E Skowronski… - Journal of …, 1998 - Am Soc Microbiol
The complete nucleotide sequence and gene organization of the three virulence plasmids
from Yersinia pestis KIM5 were determined. Plasmid pPCP1 (9,610 bp) has a GC content of …

Delayed inflammatory response to primary pneumonic plague occurs in both outbred and inbred mice

SS Bubeck, AM Cantwell, PH Dube - Infection and immunity, 2007 - Am Soc Microbiol
Yersinia pestis is the causative agent of plague, a disease that can manifest as either
bubonic or pneumonic plague. An interesting feature of plague is that it is a rapidly …

Characterization of Chromosomal Regions Conserved in Yersinia pseudotuberculosis and Lost by Yersinia pestis

F Pouillot, C Fayolle, E Carniel - Infection and immunity, 2008 - Am Soc Microbiol
The transformation of the enteropathogenic bacterium Yersinia pseudotuberculosis into the
plague bacillus, Yersinia pestis, has been accompanied by extensive genetic loss. This …

Pathogenesis of Yersinia pestis Infection in BALB/c Mice: Effects on Host Macrophages and Neutrophils

RA Lukaszewski, DJ Kenny, R Taylor… - Infection and …, 2005 - Am Soc Microbiol
The pathogenesis of infection with Yersinia pestis, the causative agent of plague, was
examined following subcutaneous infection of BALB/c mice with a fully virulent strain …