Addressing the analytic challenges of cross-sectional pediatric pneumonia etiology data

LL Hammitt, DR Feikin, JAG Scott… - Clinical infectious …, 2017 - academic.oup.com
Despite tremendous advances in diagnostic laboratory technology, identifying the pathogen
(s) causing pneumonia remains challenging because the infected lung tissue cannot usually …

The enduring challenge of determining pneumonia etiology in children: considerations for future research priorities

DR Feikin, LL Hammitt, DR Murdoch… - Clinical infectious …, 2017 - academic.oup.com
Pneumonia kills more children each year worldwide than any other disease. Nonetheless,
accurately determining the causes of childhood pneumonia has remained elusive. Over the …

Specimen collection for the diagnosis of pediatric pneumonia

LL Hammitt, DR Murdoch, JAG Scott… - Clinical infectious …, 2012 - academic.oup.com
Diagnosing the etiologic agent of pneumonia has an essential role in ensuring the most
appropriate and effective therapy for individual patients and is critical to guiding the …

Laboratory methods for determining pneumonia etiology in children

DR Murdoch, KL O'Brien, AJ Driscoll… - Clinical infectious …, 2012 - academic.oup.com
Laboratory diagnostics are a core component of any pneumonia etiology study. Recent
advances in diagnostic technology have introduced newer methods that have greatly …

Approach to identifying causative pathogens of community-acquired pneumonia in children using culture, molecular, and serology tests

Y Mardian, A Menur Naysilla, D Lokida, H Farida… - Frontiers in …, 2021 - frontiersin.org
Determining the causative pathogen (s) of community-acquired pneumonia (CAP) in
children remains a challenge despite advances in diagnostic methods. Currently available …

Use and evaluation of molecular diagnostics for pneumonia etiology studies

N Bhat, KL O'Brien, RA Karron… - Clinical infectious …, 2012 - academic.oup.com
Comprehensive microbiological testing will be a core function of the Pneumonia Etiology
Research for Child Health (PERCH) project. The development stage of PERCH provided the …

A literature review and survey of childhood pneumonia etiology studies: 2000–2010

Z Gilani, YD Kwong, OS Levine… - Clinical infectious …, 2012 - academic.oup.com
Abstract The Pneumonia Etiology Research for Child Health (PERCH) project is the largest
multicountry etiology study of childhood pneumonia since the Board on Science and …

Limited utility of polymerase chain reaction in induced sputum specimens for determining the causes of childhood pneumonia in resource-poor settings: findings from …

DM Thea, P Seidenberg, DE Park… - Clinical Infectious …, 2017 - academic.oup.com
Background. Sputum examination can be useful in diagnosing the cause of pneumonia in
adults but is less well established in children. We sought to assess the diagnostic utility of …

Etiology of childhood pneumonia: what we know, and what we need to know! Based on 5th Dr. IC Verma Excellence Oration Award

JL Mathew - The Indian Journal of Pediatrics, 2018 - Springer
Childhood community acquired pneumonia continues to be an important clinical problem at
the individual, institutional and community levels. Determination of microbial etiology is …

Editorial Commentary: The Modern Quest for the “Holy Grail” of Pneumonia Etiology

S Jain, AT Pavia - Clinical Infectious Diseases, 2016 - academic.oup.com
Defining the etiology of pneumonia is a messy business. Blood cultures are considered the
“gold standard” for bacterial pneumonia but have low sensitivity, yielding a causative …