Transcriptome-Wide Dynamics of m6A mRNA Methylation During Porcine Spermatogenesis

Z Liu, X Chen, P Zhang, F Li, L Zhang… - Genomics …, 2023 - academic.oup.com
Spermatogenesis is a continual process that occurs in the testes, in which diploid
spermatogonial stem cells (SSCs) differentiate and generate haploid spermatozoa. This …

Transcriptome-Wide m6A analysis provides novel insights into testicular development and spermatogenesis in xia-nan cattle

S Liu, X Ma, T Yue, Z Wang, K Qi, J Li, F Lin… - Frontiers in Cell and …, 2021 - frontiersin.org
Testis is the primary organ of the male reproductive tract in mammals that plays a substantial
role in spermatogenesis. Improvement of our knowledge regarding the molecular …

Comprehensive analysis of the transcriptome-wide m6A methylation in mouse pachytene spermatocytes and round spermatids

S Hong, X Shen, J Cheng, H Tang, F Sun - Frontiers in Genetics, 2022 - frontiersin.org
Spermatogenesis, an efficient and complex system in male germline development, requires
a series of elaborately regulated genetic events in which diploid spermatogonia differentiate …

Characterization of sexual maturity-associated N6-methyladenosine in boar testes

P Zhang, F Zhang, H Sui, X Yang, Y Ji, S Zheng, W Li… - BMC genomics, 2024 - Springer
Background The health and size of the testes are crucial for boar fertility. Testicular
development is tightly regulated by epigenetics. N6-methyladenosine (m6A) modification is …

Comprehensive Analysis of the Transcriptome-Wide m6A Methylome in Shaziling Pig Testicular Development

C Chen, X Tang, S Yan, A Yang, J Xiang… - International Journal of …, 2023 - mdpi.com
RNA N 6-methyladenosine (m6A) modification is one of the principal post-transcriptional
modifications and plays a dynamic role in testicular development and spermatogenesis …

Characterization of N6-methyladenosine in cattle-yak testis tissue

X Wang, J Pei, S Guo, M Cao, Y Kang… - Frontiers in Veterinary …, 2022 - frontiersin.org
N6-methyladenosine (m6A) is the most common form of eukaryotic mRNA modification, and
it has been shown to exhibit broad regulatory activity in yeast, plants, and mammals. The …

Mettl3-/Mettl14-mediated mRNA N6-methyladenosine modulates murine spermatogenesis

Z Lin, PJ Hsu, X Xing, J Fang, Z Lu, Q Zou, KJ Zhang… - Cell research, 2017 - nature.com
Spermatogenesis is a differentiation process during which diploid spermatogonial stem cells
(SSCs) produce haploid spermatozoa. This highly specialized process is precisely …

Characterization of N6-Methyladenosine in Domesticated Yak Testes Before and After Sexual Maturity

X Wang, J Pei, S Guo, M Cao, P Bao… - Frontiers in Cell and …, 2021 - frontiersin.org
The potential regulatory role of N6-methyladenosine (m6A), the most prominent mRNA
modification in eukaryotes, has recently been identified in mammals, plants, and yeast …

Meclofenamic acid represses spermatogonial proliferation through modulating m6A RNA modification

T Huang, J Guo, Y Lv, Y Zheng, T Feng, Q Gao… - Journal of animal …, 2019 - Springer
Abstract Background N6-Methyladenosine (m 6 A), the most prevalent modification in
mammalian mRNA, plays important roles in numerous biological processes. Several m 6 A …

The m6A methylation regulates gonadal sex differentiation in chicken embryo

J Li, X Zhang, X Wang, C Sun, J Zheng, J Li… - Journal of Animal …, 2022 - Springer
Background As a ubiquitous reversible epigenetic RNA modification, N6-methyladenosine
(m6A) plays crucial regulatory roles in multiple biological pathways. However, its functional …