Exosomes in brain diseases: Pathogenesis and therapeutic targets

Q Si, L Wu, D Pang, P Jiang - MedComm, 2023 - Wiley Online Library
Exosomes are extracellular vesicles with diameters of about 100 nm that are naturally
secreted by cells into body fluids. They are derived from endosomes and are wrapped in …

[HTML][HTML] Exosomes: potential targets for the diagnosis and treatment of neuropsychiatric disorders

H Li, Y Yuan, Q Xie, Z Dong - Journal of Translational Medicine, 2024 - Springer
The field of neuropsychiatry is considered a middle ground between neurological and
psychiatric disorders, thereby bridging the conventional boundaries between matter and …

Introduction to exosome and its role in brain disorders

H Sharma, HK Rachamalla, N Mishra… - Exosomes Based Drug …, 2024 - Springer
Exosomes, which are small extracellular vehicles produced by a variety of cell types, have
emerged as key actors in intercellular communication due to their ability to transport a …

[HTML][HTML] Role of exosomes in central nervous system diseases

W Liu, X Bai, A Zhang, J Huang, S Xu… - Frontiers in molecular …, 2019 - frontiersin.org
There are many types of intercellular communication, and extracellular vesicles are one of
the important forms of this. They are released by a variety of cell types, are heterogeneous …

Exosomes in neurologic and psychiatric disorders

I Tsilioni, S Panagiotidou, TC Theoharides - Clinical therapeutics, 2014 - Elsevier
Purposes The purposes of this review were to discuss the role of exosomes in neurologic
and psychiatric diseases and to propose future therapeutic approaches. Methods PubMed …

[HTML][HTML] Function of exosomes in neurological disorders and brain tumors

L Xiao, S Hareendran, YP Loh - Extracellular vesicles and …, 2021 - ncbi.nlm.nih.gov
Exosomes are a subtype of extracellular vesicles released from different cell types including
those in the nervous system, and are enriched in a variety of bioactive molecules such as …

[HTML][HTML] Exosomes: origins and therapeutic potential for neurodegenerative disease

DK Sarko, CE McKinney - Frontiers in neuroscience, 2017 - frontiersin.org
Exosomes, small lipid bilayer vesicles, are part of the transportable cell secretome that can
be taken up by nearby recipient cells or can travel through the bloodstream to cells in distant …

[HTML][HTML] The emerging role of exosomes in mental disorders

S Saeedi, S Israel, C Nagy, G Turecki - Translational psychiatry, 2019 - nature.com
Exosomes are a class of extracellular vesicles of endocytic origin, which are released by
cells and are accessible in biofluids, such as saliva, urine, and plasma. These vesicles are …

Strategies for engineering exosomes and their applications in drug delivery

M Zhu, S Li, S Li, H Wang, J Xu… - Journal of Biomedical …, 2021 - ingentaconnect.com
Exosomes are representative of a promising vehicle for delivery of biomolecules. Despite
their discovery nearly 40 years, knowledge of exosomes and extracellular vesicles (EVs) …

[HTML][HTML] Exosome as drug delivery system: Current advancements

V Sharma, CD Mukhopadhyay - Extracellular Vesicle, 2024 - Elsevier
Exosomes are nanovesicles released from cells due to pathophysiological events. These
nanoparticles are resistant to metabolic destruction and can transcend the blood-brain …