Background Persistent infection with hepatitis C virus (HCV) causes profound alterations of
the cytokine and chemokine milieu in peripheral blood. However, it is unknown to what …

Immune responses against hepatitis C virus (HCV) play a crucial role in the pathogenesis of
chronic hepatitis C. HCV infection often persists and leads to chronic hepatitis and …

Hepatitis C virus (HCV) infection is a global health concern affecting millions worldwide.
Chronic HCV infection often leads to liver inflammation and can progress to cirrhosis and …

ABSTRACT The chemokine CXCL-8 (interleukin-8) is induced by many viruses, including
hepatitis C virus (HCV). In the current study, we examined CXCL-8 levels in the context of …

Hepatitis C virus (HCV)–mediated chronic liver disease is a serious health problem around
the world and often causes fibrosis/cirrhosis and hepatocellular carcinoma. The mechanism …

The mononuclear phagocyte system (MPS), which consists of monocytes, dendritic cells
(DCs), and macrophages, plays a vital role in the innate immune defense against …

OBJECTIVE: Chemokine receptor and its ligand participate in viral immunity and HCV
infection, which are important inflammatory mediators. The current study showed the …

BACKGROUND: The mechanisms leading to hepatic injury in chronic hepatitis C virus
(HCV) infection are only incompletely understood. Recent data propose a correlation of the …

Treatment of chronic hepatitis C virus (HCV) infection with direct‐acting antivirals results in a
rapid decline in viral load and markers of hepatic inflammation, including serum chemokine …

The infiltration of various immune cell populations, including monocytes/macrophages,
natural killer (NK), NKT cells and T cells, is a central pathogenic feature following acute-and …