During sensitive and critical periods, the brain undergoes significant plasticity from the level
of individual synapses and neuronal networks up to the level of behaviour. Both sensitive …

Many neurodevelopmental disorders (NDDs) are characterized by age-dependent symptom
onset and regression, particularly during early postnatal periods of life. The neurobiological …

Descriptive studies have established that the developmental events responsible for the
assembly of neural systems and circuitry are conserved across mammalian species …

Brain development is a remarkable process. Progenitor cells are born, differentiate, and
migrate to their final locations. Axons and dendrites branch and form important synaptic …

Abnormalities in brain development, thought to be irreversible in adults, have long been
assumed to underlie the neurological and psychiatric symptoms associated with …

Cerebral cortical development occurs in precisely-timed stages that can be divided into
neurogenesis, neuronal migration and neuronal differentiation. These events occur during …

Neuronal circuits are shaped by experience during 'critical periods' of early postnatal life.
The ability to control the timing, duration, and closure of these heightened levels of brain …

Cortical circuits in the brain are refined by experience during critical periods early in
postnatal life. Critical periods are regulated by the balance of excitatory and inhibitory (E/I) …

Research on critical periods of brain development is greatly expanding our understanding of
the cellular and molecular mechanisms underlying the epochs of heightened plasticity …

Is a dog ever too old to learn new tricks? We review recent findings on sensitive periods in
brain development, ranging from sensory processing to high-level cognitive abilities in …