Autophagy and tumorigenesis
Autophagy is a catabolic process that captures cellular waste and degrades them in the
lysosome. The main functions of autophagy are quality control of cytosolic proteins and …
lysosome. The main functions of autophagy are quality control of cytosolic proteins and …
Role of autophagy in cancer and tumor progression
Autophagy, which is constitutively executed at basal level in all cells, promotes cellular
homeostasis by regulating organelles and proteins turnover. In tumor cells, autophagy is …
homeostasis by regulating organelles and proteins turnover. In tumor cells, autophagy is …
The evolving, multifaceted roles of autophagy in cancer
J Liu, J Debnath - Advances in cancer research, 2016 - Elsevier
Autophagy is a lysosomal degradation process crucial for adaptation to stress and cellular
homeostasis. In cancer, autophagy has been demonstrated to serve multifaceted roles in …
homeostasis. In cancer, autophagy has been demonstrated to serve multifaceted roles in …
Molecular mechanisms of autophagy in cancer development, progression, and therapy
VAM Vitto, S Bianchin, AA Zolondick, G Pellielo… - Biomedicines, 2022 - mdpi.com
Autophagy is an evolutionarily conserved and tightly regulated process that plays an
important role in maintaining cellular homeostasis. It involves regulation of various genes …
important role in maintaining cellular homeostasis. It involves regulation of various genes …
Autophagy and autophagy-related pathways in cancer
Maintenance of protein homeostasis and organelle integrity and function is critical for
cellular homeostasis and cell viability. Autophagy is the principal mechanism that mediates …
cellular homeostasis and cell viability. Autophagy is the principal mechanism that mediates …
Autophagy as a therapeutic target in cancer
N Chen, V Karantza - Cancer biology & therapy, 2011 - Taylor & Francis
Autophagy is a self-catabolic process that maintains intracellular homeostasis and prolongs
cell survival under stress via lysosomal degradation of cytoplasmic constituents and …
cell survival under stress via lysosomal degradation of cytoplasmic constituents and …
The role of autophagy in cancer
N Santana-Codina, JD Mancias… - Annual Review of …, 2017 - annualreviews.org
Autophagy is a highly conserved and regulated process that targets proteins and damaged
organelles for lysosomal degradation to maintain cell metabolism, genomic integrity, and …
organelles for lysosomal degradation to maintain cell metabolism, genomic integrity, and …
[HTML][HTML] Autophagy and cancer
SZ Lu, DD Harrison-Findik - World journal of biological chemistry, 2013 - ncbi.nlm.nih.gov
Autophagy is a homeostatic and evolutionarily conserved mechanism of self-digestion by
which the cells degrade and recycle long-lived proteins and excess or damaged organelles …
which the cells degrade and recycle long-lived proteins and excess or damaged organelles …
Autophagy: cancer's friend or foe?
The functional relevance of autophagy in tumor formation and progression remains
controversial. Autophagy can promote tumor suppression during cancer initiation and …
controversial. Autophagy can promote tumor suppression during cancer initiation and …