Photodynamic therapy with nanoparticles to combat microbial infection and resistance

A Bekmukhametova, H Ruprai, JM Hook, D Mawad… - Nanoscale, 2020 - pubs.rsc.org
Infections caused by drug-resistant pathogens are rapidly increasing in incidence and pose
an urgent global health concern. New treatments are needed to address this critical situation …

Antibacterial nanophotosensitizers in photodynamic therapy: An update

Z Badran, B Rahman, P De Bonfils, P Nun… - Drug Discovery …, 2023 - Elsevier
Highlights•The WHO is seriously concerned about bacterial infections resistance in clinical
medicine.•Antibacterial Photodynamic Therapy (aPDT) represents a promising alternative to …

Nanomaterials enabling clinical translation of antimicrobial photodynamic therapy

M Awad, N Thomas, TJ Barnes, CA Prestidge - Journal of Controlled …, 2022 - Elsevier
Antimicrobial photodynamic therapy (aPDT) has emerged as a promising approach to aid
the fight against looming antibiotic resistance. aPDT harnesses the energy of light through …

Design of photosensitizing agents for targeted antimicrobial photodynamic therapy

M Klausen, M Ucuncu, M Bradley - Molecules, 2020 - mdpi.com
Photodynamic inactivation of microorganisms has gained substantial attention due to its
unique mode of action, in which pathogens are unable to generate resistance, and due to …

Conjugating biomaterials with photosensitizers: Advances and perspectives for photodynamic antimicrobial chemotherapy

N Maldonado-Carmona, TS Ouk… - Photochemical & …, 2020 - pubs.rsc.org
Antimicrobial resistance is threatening to overshadow last century's medical advances.
Previously eradicated infectious diseases are now resurgent as multi-drug resistant strains …

Nanoparticles: their potential use in antibacterial photodynamic therapy

S Perni, P Prokopovich, J Pratten, IP Parkin… - Photochemical & …, 2011 - Springer
Photodynamic therapy (PDT) has been proposed as a new technique to inactivate
microorganisms as it does not lead to the selection of mutant resistant strains; a clear benefit …

Biofilm‐sensitive photodynamic nanoparticles for enhanced penetration and antibacterial efficiency

S Wu, C Xu, Y Zhu, L Zheng, L Zhang… - Advanced Functional …, 2021 - Wiley Online Library
Efficient antimicrobials are urgently needed for the treatment of bacterial biofilms due to their
resistance to traditional drugs. Photodynamic therapy (PDT) is a new strategy that has been …

Natural photosensitizers in antimicrobial photodynamic therapy

E Polat, K Kang - Biomedicines, 2021 - mdpi.com
Health problems and reduced treatment effectiveness due to antimicrobial resistance have
become important global problems and are important factors that negatively affect life …

Antimicrobial photodynamic inactivation in nanomedicine: small light strides against bad bugs

R Yin, T Agrawal, U Khan, GK Gupta, V Rai… - …, 2015 - Future Medicine
The relentless advance of drug-resistance among pathogenic microbes, mandates a search
for alternative approaches that will not cause resistance. Photodynamic inactivation (PDI) …

Rejuvenated photodynamic therapy for bacterial infections

Q Jia, Q Song, P Li, W Huang - Advanced healthcare materials, 2019 - Wiley Online Library
The emergence of multidrug resistant bacterial strains has hastened the exploration of
advanced microbicides and antibacterial techniques. Photodynamic antibacterial therapy …