Genetics of the quantitative Lp (a) lipoprotein trait: III. Contribution of Lp (a) glycoprotein phenotypes to normal lipid variation
E Boerwinkle, HJ Menzel, HG Kraft, G Utermann - Human genetics, 1989 - Springer
Summary Apolipoprotein (a)[apo (a)] is a large serum glycoprotein with several genetically
determined isoforms differing in their apparent molecular weight. We determined the effects …
determined isoforms differing in their apparent molecular weight. We determined the effects …
Apolipoprotein (a) gene accounts for greater than 90% of the variation in plasma lipoprotein (a) concentrations.
E Boerwinkle, CC Leffert, J Lin… - The Journal of …, 1992 - Am Soc Clin Investig
Plasma lipoprotein (a)[Lp (a)], a low density lipoprotein particle with an attached
apolipoprotein (a)[apo (a)], varies widely in concentration between individuals. These …
apolipoprotein (a)[apo (a)], varies widely in concentration between individuals. These …
The apolipoprotein (a) gene: a transcribed hypervariable locus controlling plasma lipoprotein (a) concentration
HG Kraft, S Köchl, HJ Menzel, C Sandholzer… - Human genetics, 1992 - Springer
Abstract Lipoprotein (a)[Lp (a)] is a quantitative trait in human plasma. Lp (a) consists of a
low-density lipoprotein and the plasminogen-related apolipoprotein (a)[apo (a)]. The apo (a) …
low-density lipoprotein and the plasminogen-related apolipoprotein (a)[apo (a)]. The apo (a) …
Variation in lipoprotein (a) concentration associated with different apolipoprotein (a) alleles.
YF Perombelon, AK Soutar… - The Journal of clinical …, 1994 - Am Soc Clin Investig
Plasma lipoprotein (a)(Lp (a)) concentrations vary considerably between individuals. To
examine the variation for products of the same and different apolipoprotein (a)(apo (a)) …
examine the variation for products of the same and different apolipoprotein (a)(apo (a)) …
Studies on apolipoprotein (a) phenotypes. Part 1. Phenotype frequencies in a healthy Japanese population
A Abe, A Noma - Atherosclerosis, 1992 - Elsevier
The frequency distribution for serum lipoprotein (a)(Lp (a)) concentrations in healthy
Japanese was highly skewed, with a mean±SD of 14.6±13.6 mg/dl and a median of 11.0 …
Japanese was highly skewed, with a mean±SD of 14.6±13.6 mg/dl and a median of 11.0 …
Sequence polymorphisms in the apolipoprotein (a) gene. Evidence for dissociation between apolipoprotein (a) size and plasma lipoprotein (a) levels.
JC Cohen, G Chiesa, HH Hobbs - The Journal of clinical …, 1993 - Am Soc Clin Investig
Apolipoprotein (a)[apo (a)], an apolipoprotein unique to lipoprotein (a)[Lp (a)], is highly
polymorphic in size. Previous studies have indicated that the size of the apo (a) gene tends …
polymorphic in size. Previous studies have indicated that the size of the apo (a) gene tends …
Polymorphic forms of human apolipoprotein [a]: inheritance and relationship of their molecular weights to plasma levels of lipoprotein [a].
JW Gaubatz, KI Ghanem, J Guevara, ML Nava… - Journal of Lipid …, 1990 - ASBMB
The plasma concentration of human lipoprotein [a], Lp [a], is highly correlated with coronary
artery disease. The protein moiety of Lp [a], apoLp [a], consists of two apoproteins, apo [a] …
artery disease. The protein moiety of Lp [a], apoLp [a], consists of two apoproteins, apo [a] …
Apolipoprotein (a) alleles determine lipoprotein (a) particle density and concentration in plasma.
HG Kraft, C Sandholzer, HJ Menzel… - … and Thrombosis: A …, 1992 - Am Heart Assoc
The distribution of Lp (a) lipoprotein (Lp [a]) and genetic apolipoprotein (a)(apo [a]) isoforms
in plasma samples from 29 healthy normolipidemic subjects of known apo (a) phenotype …
in plasma samples from 29 healthy normolipidemic subjects of known apo (a) phenotype …
Expressed hypervariable polymorphism of apolipoprotein (a).
MI Kamboh, RE Ferrell, BA Kottke - American journal of human …, 1991 - ncbi.nlm.nih.gov
Elevated plasma lipoprotein (a)(LP (a] levels are an independent predictor of the
development of premature atherosclerosis in humans. The LP (a) particle consists of two …
development of premature atherosclerosis in humans. The LP (a) particle consists of two …
Effects of the apolipoprotein (a) size polymorphism on the lipoprotein (a) concentration in 7 ethnic groups
C Sandholzer, DM Hallman, N Saha, G Sigurdsson… - Human genetics, 1991 - Springer
Summary Apolipoprotein (a)[apo (a)] exhibits a genetic size polymorphism explaining about
40% of the variability in lipoprotein (a)[Lp (a)] concentration in Tyroleans. Lp (a) …
40% of the variability in lipoprotein (a)[Lp (a)] concentration in Tyroleans. Lp (a) …