Background: Maternal factors are implicated in the onset of childhood asthma. Differentiation
of naïve CD4+ T lymphocytes into pro-allergic T-helper 2 cells induces interleukin (IL) 4 …

Background: Polycyclic aromatic hydrocarbons (PAHs) are carcinogenic environmental
pollutants generated during incomplete combustion. After exposure and during metabolism …

Background Prenatal exposure to polycyclic aromatic hydrocarbons (PAHs) is a potential
risk factor for adverse birth outcomes. Epigenetic mechanisms may play a key role in which …

Polycyclic aromatic hydrocarbons (PAHs), as a kind of endocrine disruptors, can enter the
fetus body cross the placental barrier from prenatal PAHs exposure to cause adverse birth …

Background Polycyclic aromatic hydrocarbons (PAH) are carcinogenic, neurotoxic
environmental pollutants generated during incomplete combustion of fossil fuel and other …

Growing evidence indicates that prenatal exposure to maternal smoking is a risk factor for
the development of asthma in children. However, the effects of prenatal environmental …

Background Ambient air pollutant (AAP) exposure is associated with adverse pregnancy
outcomes, such as preeclampsia, preterm labor, and low birth weight. Previous studies have …

In a longitudinal cohort of∼ 700 children in New York City, the prevalence of asthma (>
25%) is among the highest in the US. This high risk may in part be caused by transplacental …

Maternal prenatal exposures, including bisphenol A (BPA), are associated with offspring's
risk of disease later in life. Alterations in DNA methylation may be a mechanism through …

Background Evidence suggests that exposure to polycyclic aromatic hydrocarbons (PAH s)
increases atopy; it is unclear how PAH exposure is linked to increased severity of atopic …