[HTML][HTML] Is histone acetylation the most important physiological function for CBP and p300?
DC Bedford, PK Brindle - Aging (Albany NY), 2012 - ncbi.nlm.nih.gov
Protein lysine acetyltransferases (HATs or PATs) acetylate histones and other proteins, and
are principally modeled as transcriptional coactivators. CREB binding protein (CBP …
are principally modeled as transcriptional coactivators. CREB binding protein (CBP …
p300/CBP proteins: HATs for transcriptional bridges and scaffolds
HM Chan, NB La Thangue - Journal of cell science, 2001 - journals.biologists.com
p300/CBP transcriptional co-activator proteins play a central role in co-ordinating and
integrating multiple signal-dependent events with the transcription apparatus, allowing the …
integrating multiple signal-dependent events with the transcription apparatus, allowing the …
[HTML][HTML] The transcriptional coactivators p300 and CBP are histone acetyltransferases
VV Ogryzko, RL Schiltz, V Russanova, BH Howard… - Cell, 1996 - cell.com
Abstract p300/CBP is a transcriptional adaptor that integrates signals from many sequence-
specific activators via direct interactions. Various cellular and viral factors target p300/CBP to …
specific activators via direct interactions. Various cellular and viral factors target p300/CBP to …
Target gene context influences the transcriptional requirement for the KAT3 family of CBP and p300 histone acetyltransferases
DC Bedford, LH Kasper, T Fukuyama, PK Brindle - Epigenetics, 2010 - Taylor & Francis
One general principle of gene regulation is that DNA-binding transcription factors modulate
transcription by recruiting cofactors that modify histones and chromatin structure. A second …
transcription by recruiting cofactors that modify histones and chromatin structure. A second …
The structural basis of protein acetylation by the p300/CBP transcriptional coactivator
X Liu, L Wang, K Zhao, PR Thompson, Y Hwang… - Nature, 2008 - nature.com
The transcriptional coactivator p300/CBP (CREBBP) is a histone acetyltransferase (HAT)
that regulates gene expression by acetylating histones and other transcription factors …
that regulates gene expression by acetylating histones and other transcription factors …
CBP/p300 histone acetyl-transferase activity is important for the G1/S transition
S Ait-Si-Ali, A Polesskaya, S Filleur, R Ferreira… - Oncogene, 2000 - nature.com
Transforming viral proteins such as E1A which force quiescent cells into S phase have two
essential cellular target proteins, Rb and CBP/p300. Rb regulates the G1/S transition by …
essential cellular target proteins, Rb and CBP/p300. Rb regulates the G1/S transition by …
Quantitative analysis of CBP-and P300-induced histone acetylations in vivo using native chromatin
KJ McManus, MJ Hendzel - Molecular and cellular biology, 2003 - Taylor & Francis
In vivo, histone tails are involved in numerous interactions, including those with DNA,
adjacent histones, and other, nonhistone proteins. The amino termini are also the substrates …
adjacent histones, and other, nonhistone proteins. The amino termini are also the substrates …
Double null cells reveal that CBP and p300 are dispensable for p53 targets p21 and Mdm2 but variably required for target genes of other signaling pathways
LH Kasper, MC Thomas, GP Zambetti, PK Brindle - Cell cycle, 2011 - Taylor & Francis
The histone acetyltransferase coactivators CBP (CREBBP) and p300 (EP300) have more
than 400 described protein interaction partners and are implicated in numerous …
than 400 described protein interaction partners and are implicated in numerous …
Histone acetyltransferase activities of cAMP-regulated enhancer-binding protein and p300 in tissues of fetal, young, and old mice
Q Li, H Xiao, K Isobe - The Journals of Gerontology Series A …, 2002 - academic.oup.com
CBP, a protein that binds to cyclic adenosine monophosphate-regulated enhancer-binding
protein, and homologue protein, p300, have histone acetyltransferase (HAT) activity and are …
protein, and homologue protein, p300, have histone acetyltransferase (HAT) activity and are …
[PDF][PDF] Developmentally regulated expression of the transcriptional cofactors/histone acetyltransferases CBP and p300 during mouse embryogenesis
M Partanen, J Motoyama, CC Hui - International Journal of …, 1999 - scholar.archive.org
ABSTRACT CBP (CREBBP/CREB-binding protein) and p300 are related signal-dependent
transcriptional cofactors and histone acetyltransferases. They are both implicated in …
transcriptional cofactors and histone acetyltransferases. They are both implicated in …