Quantitative proteomic analysis of hepatocyte-secreted extracellular vesicles reveals candidate markers for liver toxicity
E Rodríguez-Suárez, E Gonzalez, C Hughes… - Journal of …, 2014 - Elsevier
Extracellular vesicles have created great interest as possible source of biomarkers for
different biological processes and diseases. Although the biological function of these …
different biological processes and diseases. Although the biological function of these …
Candidate biomarkers in exosome‐like vesicles purified from rat and mouse urine samples
J Conde‐Vancells, E Rodriguez‐Suarez… - PROTEOMICS …, 2010 - Wiley Online Library
Purpose: There is a compelling clinical imperative to identify discerning molecular
biomarkers of hepatic disease in order to inform the diagnosis, prognosis and treatment …
biomarkers of hepatic disease in order to inform the diagnosis, prognosis and treatment …
Best practice of identification and proteomic analysis of extracellular vesicles in human health and disease
Introduction: Extracellular vesicles are emerging sources of biomarkers for modern
preventive and precision medicine. Extracellular vesicles in body fluids offer a unique …
preventive and precision medicine. Extracellular vesicles in body fluids offer a unique …
Characterization and comprehensive proteome profiling of exosomes secreted by hepatocytes
J Conde-Vancells, E Rodriguez-Suarez… - Journal of proteome …, 2008 - ACS Publications
Exosomes represent a discrete population of vesicles that are secreted from various cell
types to the extracellular media. Their protein and lipid composition are a consequence of …
types to the extracellular media. Their protein and lipid composition are a consequence of …
[HTML][HTML] Extracellular Vesicles as Markers of Liver Function: Optimized Workflow for Biomarker Identification in Liver Disease
M Paluschinski, S Loosen, C Kordes, V Keitel… - International Journal of …, 2023 - mdpi.com
Liver diseases represent a significant global health burden, necessitating the development
of reliable biomarkers for early detection, prognosis, and therapeutic monitoring …
of reliable biomarkers for early detection, prognosis, and therapeutic monitoring …
Extracellular vesicles as biomarkers in liver diseases: A clinician's point of view
S Thietart, PE Rautou - Journal of hepatology, 2020 - Elsevier
Extracellular vesicles are membrane-bound vesicles containing proteins, lipids, RNAs and
microRNAs. They can originate from both healthy and stressed cells, and provide a …
microRNAs. They can originate from both healthy and stressed cells, and provide a …
[HTML][HTML] Transcriptome of extracellular vesicles released by hepatocytes
F Royo, K Schlangen, L Palomo, E Gonzalez… - PloS one, 2013 - journals.plos.org
The discovery that the cells communicate through emission of vesicles has opened new
opportunities for better understanding of physiological and pathological mechanisms. This …
opportunities for better understanding of physiological and pathological mechanisms. This …
Isolation of extracellular vesicles for proteomic profiling
Extracellular vesicles are nano-sized lipid bilayer vesicles released from most cells,
including archaea, bacteria, and eukaryotic cells. These membrane vesicles play multiple …
including archaea, bacteria, and eukaryotic cells. These membrane vesicles play multiple …
Circulating extracellular vesicles as a potential source of new biomarkers of drug-induced liver injury
X Yang, Z Weng, DL Mendrick, Q Shi - Toxicology letters, 2014 - Elsevier
Like most cell types, hepatocytes constantly produce extracellular vesicles (EVs) such as
exosomes and microvesicles that are released into the circulation to transport signaling …
exosomes and microvesicles that are released into the circulation to transport signaling …
Proteomic and bioinformatics analyses of mouse liver microsomes
F Peng, X Zhan, MY Li, F Fang, G Li, C Li… - … journal of proteomics, 2012 - Wiley Online Library
Microsomes are derived mostly from endoplasmic reticulum and are an ideal target to
investigate compound metabolism, membrane‐bound enzyme functions, lipid‐protein …
investigate compound metabolism, membrane‐bound enzyme functions, lipid‐protein …
相关搜索
- liver toxicity candidate markers
- extracellular vesicles candidate markers
- extracellular vesicles liver toxicity
- extracellular vesicles proteomic analysis
- extracellular vesicles biomarker identification
- extracellular vesicles clinician's point
- extracellular vesicles optimized workflow
- human health proteomic analysis
- extracellular vesicles human health
- extracellular vesicles liver function
- extracellular vesicles liver diseases
- extracellular vesicles liver injury
- extracellular vesicles proteomic profiling