Pendred's syndrome is an autosomal-recessive disorder characterized by deafness and
goiter. After our recent identification of the human gene mutated in Pendred's syndrome …

Immunolocalization studies of mouse cochlea and vestibular end-organ were performed to
study the expression pattern of pendrin, the protein encoded by the Pendred syndrome gene …

The disease gene for Pendred syndrome has been recently characterized and named PDS.
It codes for a transmembrane protein called pendrin, which is highly expressed at the apical …

Pendrin is an anion transporter encoded by the PDS/Pds gene. In humans, mutations in
PDS cause the genetic disorder Pendred syndrome, which is associated with deafness and …

Following the positional cloning of PDS, the gene mutated in the deafness/goitre disorder
Pendred syndrome (PS), numerous studies have focused on defining the role of PDS in …

Pendred syndrome (PS) is the most frequent form of genetically related syndromic hearing
loss, and is associated with mutations of pendrin, encoded by the SLC26A4 gene. This …

Pendred syndrome, characterized by congenital sensorineural hearing loss and goiter, is
one of the most common forms of syndromic deafness. The gene causing Pendred …

The PDS gene encodes a transmembrane protein, known as pendrin, which functions as a
transporter of iodide and chloride. Mutations in this gene are responsible for Pendred …

Pendred syndrome comprises congenital sensorineural hearing loss, thyroid goiter, and
positive perchlorate discharge test. Recently, this autosomal recessive disorder was shown …

Pendred's syndrome is an autosomal recessive disorder characterized by sensorineural
deafness, goiter, and impaired iodide organification. It is caused by mutations in the …