Advances in the treatment of acute myeloid leukemia: new drugs and new challenges

NJ Short, M Konopleva, TM Kadia, G Borthakur… - Cancer discovery, 2020 - AACR
The therapeutic armamentarium of acute myeloid leukemia (AML) has rapidly expanded in
the past few years, driven largely by translational research into its genomic landscape and …

New strategies to treat AML: novel insights into AML survival pathways and combination therapies

R Nair, A Salinas-Illarena, HM Baldauf - Leukemia, 2021 - nature.com
The effective treatment of acute myeloid leukemia (AML) is very challenging. Due to the
immense heterogeneity of this disease, treating it using a “one size fits all” approach is …

[HTML][HTML] Recent advances in the understanding and treatment of acute myeloid leukemia

J Watts, S Nimer - F1000Research, 2018 - ncbi.nlm.nih.gov
Acute myeloid leukemia (AML) is a clinically and genetically heterogeneous disease that
has a poor prognosis. Recent advances in genomics and molecular biology have led to a …

Recent drug approvals for acute myeloid leukemia

C Lai, K Doucette, K Norsworthy - Journal of hematology & oncology, 2019 - Springer
Acute myeloid leukemia (AML) is the most common form of acute leukemia in adults, with an
incidence that increases with age, and a generally poor prognosis. The disease is clinically …

Precision therapy for acute myeloid leukemia

X Yang, J Wang - Journal of hematology & oncology, 2018 - Springer
Acute myeloid leukemia (AML) is a molecularly and clinically heterogeneous disease.
Despite advances in understanding the pathogenesis of AML, the standard therapy …

Advances in targeted therapy for acute myeloid leukaemia

S Kayser, MJ Levis - British journal of haematology, 2018 - Wiley Online Library
In the past few years, research in the underlying pathogenic mechanisms of acute myeloid
leukaemia (AML) has led to remarkable advances in our understanding of the disease …

Recent advances in targeted therapies in acute myeloid leukemia

RS Bhansali, KW Pratz, C Lai - Journal of Hematology & Oncology, 2023 - Springer
Acute myeloid leukemia (AML) is the most common acute leukemia in adults. While survival
for younger patients over the last several decades has improved nearly sixfold with the …

Advances in acute myeloid leukemia

LF Newell, RJ Cook - Bmj, 2021 - bmj.com
Acute myeloid leukemia (AML) is an uncommon but potentially catastrophic diagnosis with
historically high mortality rates. The standard of care treatment remained unchanged for …

Emerging agents and regimens for AML

H Liu - Journal of hematology & oncology, 2021 - Springer
Until recently, acute myeloid leukemia (AML) patients used to have limited treatment options,
depending solely on cytarabine+ anthracycline (7+ 3) intensive chemotherapy and …

[HTML][HTML] New drugs in acute myeloid leukemia

TM Kadia, F Ravandi, J Cortes, H Kantarjian - Annals of Oncology, 2016 - Elsevier
The standard therapy for acute myeloid leukemia (AML) has not changed meaningfully for
the past four decades. Improvements in supportive care and modifications to the dose and …