The female genital tract is a portal of entry for sexual HIV transmission and a possible viral
reservoir. In this study, the ectocervical CD8+ T cell distribution was explored in situ and was …

Studies using genital tissue samples from HIV-infected women might provide important
information about HIV susceptibility and transmission. In this study, ectocervical biopsies …

Plasma viral load predicts genital tract human immunodeficiency virus (HIV) shedding in HIV-
infected women. We investigated whether local mucosal T-cell activation (HLA-DR, CD38 …

Citation Shen R, Richter HE, Smith PD. Early HIV‐1 target cells in human vaginal and
ectocervical mucosa. Am J Reprod Immunol 2011; 65: 261–267 After translocation through …

Background The burden of HPV-associated premalignant and malignant cervical lesions
remains high in HIV+ women even under ART treatment. In order to identify possible …

Background Genital mucosa is the main portal of entry for various incoming pathogens,
including human immunodeficiency virus (HIV), hence it is an important site for host immune …

The female genital tract is the major route of heterosexual human immunodeficiency virus
(HIV) acquisition and transmission. Here, we investigated whether HIV-specific CD8 T-cell …

HIV‐specific T cells that produce interferon‐γ (IFN‐γ) are present in the genital tract of HIV‐
infected women although these do not provide protection against genital HIV shedding …

Background: The mucosal lymphocyte population is the largest in the body, and the
gastrointestinal compartment has been well characterized in HIV infection. Much less is …

Objective: The activation of effector immune cells at the cervicovaginal mucosa (CVM) might
influence the cervical HIV load and thus the secondary transmission; however, limited …